Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 7/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4222716 | 0.99 | HDAC1 (0.47) | HDAC1HDAC3HDAC2NCOR2UTS2R | |
| SCHEMBL2384389 | 0.97 | HDAC1 (0.47) | HDAC1HDAC3HDAC2NCOR2UTS2R | |
| SCHEMBL2384677 | 0.94 | HDAC1 (0.49) | HDAC1HDAC3HDAC2NCOR2UTS2R | |
| SCHEMBL4223952 | 0.89 | HDAC1 (0.46) | HDAC1HDAC3HDAC2NCOR2HDAC8 | |
| SCHEMBL4224028 | 0.88 | UTS2R (0.43) | HDAC1HDAC3HDAC2UTS2RHDAC8 | |
| SCHEMBL3230138 | 0.88 | UTS2R (0.47) | HDAC1HDAC3HDAC2NCOR2UTS2R | |
| SCHEMBL1497122 | 0.88 | UTS2R (0.42) | HDAC1HDAC3HDAC2NCOR2UTS2R | |
| SCHEMBL4224435 | 0.87 | HDAC1 (0.47) | HDAC1HDAC3HDAC2NCOR2UTS2R | |
| SCHEMBL3262063 | 0.87 | UTS2R (0.41) | HDAC1HDAC3HDAC2UTS2RHDAC8 | |
| SCHEMBL2386741 | 0.87 | HDAC3 (0.43) | HDAC1HDAC3HDAC2NCOR2UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |