Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 11/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4231191 | 0.93 | HDAC3 (0.44) | HDAC1HDAC3HDAC8UTS2RHDAC2 | |
| SCHEMBL4225161 | 0.91 | UTS2R (0.45) | HDAC1HDAC3HDAC8UTS2RHDAC2 | |
| SCHEMBL4224174 | 0.90 | UTS2R (0.49) | HDAC1HDAC3HDAC8UTS2RHDAC2 | |
| SCHEMBL4228771 | 0.90 | UTS2R (0.44) | HDAC1HDAC3HDAC8UTS2RHDAC2 | |
| SCHEMBL4229190 | 0.88 | UTS2R (0.43) | HDAC1HDAC3HDAC8UTS2RHDAC2 | |
| SCHEMBL4224589 | 0.88 | UTS2R (0.48) | HDAC1HDAC3HDAC8UTS2RHDAC2 | |
| SCHEMBL4224236 | 0.88 | UTS2R (0.45) | HDAC1HDAC3HDAC8UTS2RHDAC2 | |
| SCHEMBL4233206 | 0.88 | UTS2R (0.45) | HDAC1HDAC3HDAC8UTS2RHDAC2 | |
| SCHEMBL4225192 | 0.87 | UTS2R (0.46) | HDAC1HDAC3HDAC8UTS2RHDAC2 | |
| SCHEMBL4219338 | 0.87 | UTS2R (0.41) | HDAC1HDAC3HDAC8UTS2RHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |