⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4972944 | 0.98 | EPHX1 (0.52) | — | |
| SCHEMBL868764 | 0.95 | EPHX1 (0.59) | — | |
| SCHEMBL19426060 | 0.93 | EPHX1 (0.63) | — | |
| SCHEMBL15700754 | 0.93 | EPHX1 (0.63) | — | |
| SCHEMBL17169490 | 0.93 | EPHX1 (0.63) | — | |
| SCHEMBL19426065 | 0.93 | EPHX1 (0.63) | — | |
| SCHEMBL8393998 | 0.93 | EPHX1 (0.63) | — | |
| SCHEMBL1067515 | 0.93 | EPHX1 (0.63) | — | |
| Hydrochloric Acid SCHEMBL3927000 | 0.91 | EPHX1 (0.61) | — | |
| Bicarbonate SCHEMBL7105895 | 0.91 | EPHX1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118598873-B | Preparation method of chiral aza-quinoline compound | 艾斯拓康生物医药(天津)有限公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-118598873-B | Preparation method of chiral aza-quinoline compound | 艾斯拓康生物医药(天津)有限公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-118598873-A | Preparation method of chiral aza-quinoline compound | 艾斯拓康生物医药(天津)有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-118598873-A | Preparation method of chiral aza-quinoline compound | 艾斯拓康生物医药(天津)有限公司 | 2024-09-06 | — | — | CN | disclosed |
| US-20230382925-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2023-11-30 | — | — | US | disclosed |
| CN-113292535-B | Method for preparing apaluamide intermediate and apaluamide | 南京方生和医药科技有限公司 | 2022-07-01 | — | — | CN | disclosed |
| EP-3950692-A1 | NOVEL TRICYCLIC COMPOUNDS | AbbVie Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-113292535-A | Method for preparing apaluamide intermediate and apaluamide | 南京方生和医药科技有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-107266419-A | Specific amino pyridazine class, thing in combination, and its application method | 赛特凯恩蒂克公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-106986832-A | Vegfr3 inhibitor | 癌症治疗合作研究中心有限公司 | 2017-07-28 | — | — | CN | disclosed |
| US-20110251379-A1 | COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS | SATORI PHARMACEUTICALS, INC. (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110237540-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. | 2011-09-29 | — | — | US | disclosed |
| US-20110224189-A1 | SUBSTITUTED CYCLIC HYDROXAMATES AS INHIBITORS OF MATRIX METALLOPROTEINASES | INCYTE CORPORATION | 2011-09-15 | — | — | US | disclosed |
| US-20110152512-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY | CERULEAN PHARMA INC. | 2011-06-23 | — | — | US | disclosed |
| US-20090163557-A1 | Cannabinergic Lipid Ligands | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-06-25 | — | — | US | disclosed |
| CN-1930124-A | Process for cross coupling indoles | BOEHRINGER INGELHEIM PHARMA (US) | 2007-03-14 | — | — | CN | disclosed |
| CN-1791599-A | Hepatitis c inhibitor compounds | BOEHRINGER INGELHEIM INT (DE) | 2006-06-21 | — | — | CN | disclosed |
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| US-4386033-A | BOILING, CONDENSATION OF VAPORS, CIRCULATION; SEPARATION | BAYER AKTIENGESELLSCHAFT (DE) | 1983-05-31 | — | — | US | disclosed |