Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 19/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4227035 | 0.84 | SSTR5 (0.40) | SSTR5HRH1HTR2BKCNH2 | |
| SCHEMBL4224213 | 0.81 | SSTR5 (0.32) | SSTR5HRH1HTR2B | |
| SCHEMBL4234146 | 0.81 | SSTR5 (0.39) | SSTR5HRH1HTR2BKCNH2ACHE | |
| SCHEMBL4234143 | 0.78 | SSTR5 (0.38) | SSTR5HRH1HTR2BKCNH2ACHE | |
| SCHEMBL3778098 | 0.77 | SSTR5 (0.46) | SSTR5HRH1HTR2BKCNH2ACHE | |
| SCHEMBL4956137 | 0.73 | SSTR5 (0.48) | SSTR5HRH1HTR2BACHE | |
| Hydrochloric Acid SCHEMBL4375373 | 0.72 | SSTR5 (0.40) | SSTR5HRH1HTR2BKCNH2 | |
| SCHEMBL4231315 | 0.71 | SSTR5 (0.43) | SSTR5HRH1HTR2BKCNH2 | |
| SCHEMBL3776972 | 0.69 | SSTR5 (0.56) | SSTR5HRH1HTR2BKCNH2ACHE | |
| SCHEMBL3770056 | 0.67 | SSTR5 (0.58) | SSTR5HRH1HTR2BKCNH2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-B1 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | EP | disclosed |