Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 9/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3832883 | 0.93 | MEN1 (0.39) | MEN1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL4225426 | 0.88 | MEN1 (0.39) | MEN1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL4224157 | 0.86 | CASR (0.43) | ALDH1A1TSHRADORA2ACD274JAK2 | |
| SCHEMBL4225438 | 0.84 | MEN1 (0.40) | MEN1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL4234586 | 0.84 | CASR (0.43) | ALDH1A1TSHRADORA2ACD274JAK2 | |
| SCHEMBL3230179 | 0.84 | JAK2 (0.38) | ALDH1A1MAPTLMNACYP3A4PKM | |
| SCHEMBL4219747 | 0.84 | CD274 (0.41) | MAPTLMNACYP3A4PKMHTR2A | |
| SCHEMBL4224550 | 0.84 | JAK2 (0.38) | ALDH1A1MAPTGSK3BCYP3A4MAPK1 | |
| SCHEMBL3225998 | 0.83 | CD274 (0.41) | ALDH1A1MAPTKMT2ALMNAPKM | |
| SCHEMBL4220624 | 0.83 | CD274 (0.38) | ALDH1A1CYP3A4HRH3CD274JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2135620-A1 | OCULAR HYPOTENSIVE AGENT COMPRISING COMPOUND CAPABLE OF INHIBITING HISTONE DEACETYLASE AS ACTIVE INGREDIENT | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-23 | — | — | EP | disclosed |
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |