Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | F13A1 | P00488 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | THPO | P40225 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30370693 | 1.00 | TSHR (0.50) | TSHRABCC4MAPTALDH1A1LMNA | |
| SCHEMBL30366612 | 1.00 | TSHR (0.50) | TSHRABCC4MAPTALDH1A1LMNA | |
| SCHEMBL1678269 | 1.00 | TSHR (0.50) | TSHRABCC4MAPTALDH1A1LMNA | |
| SCHEMBL9282562 | 1.00 | TSHR (0.50) | TSHRABCC4MAPTALDH1A1LMNA | |
| SCHEMBL1241873 | 0.97 | TSHR (0.46) | TSHRABCC4MAPTALDH1A1LMNA | |
| SCHEMBL28457803 | 0.90 | CA12 (0.50) | TSHRMAPTALDH1A1LMNACA12 | |
| SCHEMBL22753257 | 0.88 | TSHR (0.73) | TSHRALDH1A1 | |
| SCHEMBL22117200 | 0.88 | TSHR (0.41) | TSHRABCC4MAPTALDH1A1LMNA | |
| SCHEMBL21568894 | 0.88 | TSHR (0.65) | TSHRALDH1A1LMNACYP1A2CYP2C19 | |
| SCHEMBL22117222 | 0.88 | TSHR (0.41) | TSHRABCC4MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134822-A2 | FLUORESCENT ORGANIC NANOPARTICLES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2009-11-05 | — | — | WO | disclosed |