Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944397 | 0.89 | PTPN1 (0.38) | MEN1MAPTKMT2APOLBHSD17B10 | |
| SCHEMBL3604966 | 0.82 | MEN1 (0.39) | MEN1MAPTKMT2APOLBHSD17B10 | |
| SCHEMBL3598276 | 0.75 | SLC6A2 (0.41) | MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL3600016 | 0.73 | KDM4E (0.35) | MAPTPOLBHSD17B10KDM4ESLC6A2 | |
| SCHEMBL3599855 | 0.73 | TP53 (0.42) | MEN1MAPTKMT2APOLBGAA | |
| SCHEMBL3602880 | 0.72 | SLC6A2 (0.39) | MEN1MAPTKMT2APOLBHSD17B10 | |
| SCHEMBL3608728 | 0.72 | OPRL1 (0.36) | MEN1MAPTKMT2APOLBHSD17B10 | |
| SCHEMBL3610115 | 0.71 | CA12 (0.39) | MEN1KMT2APOLBKDM4ESLC6A2 | |
| SCHEMBL4063463 | 0.71 | SLC6A2 (0.39) | MAPTPTPN1SLC6A2SLC6A4 | |
| SCHEMBL4057185 | 0.70 | MAPT (0.41) | MEN1MAPTKMT2APOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061776-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | Wyeth a Corporation of the State of Delaware (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008073459-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |