Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 20/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.53 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3769507 | 0.95 | SSTR5 (0.58) | SSTR5KCNH2SSTR3 | |
| SCHEMBL4230321 | 0.90 | SSTR5 (0.47) | SSTR5KCNH2SSTR3 | |
| SCHEMBL3777300 | 0.90 | SSTR5 (0.57) | SSTR5KCNH2SSTR3 | |
| SCHEMBL4234199 | 0.89 | SSTR5 (0.54) | SSTR5KCNH2 | |
| SCHEMBL3781606 | 0.86 | SSTR5 (0.56) | SSTR5KCNH2SSTR3 | |
| SCHEMBL3787433 | 0.86 | SSTR5 (0.56) | SSTR5KCNH2SSTR3 | |
| SCHEMBL4235821 | 0.85 | SSTR5 (0.44) | SSTR5KCNH2 | |
| SCHEMBL4235419 | 0.85 | SSTR5 (0.54) | SSTR5KCNH2 | |
| SCHEMBL3774425 | 0.85 | SSTR5 (0.51) | SSTR5KCNH2SSTR3 | |
| SCHEMBL3774871 | 0.85 | SSTR5 (0.56) | SSTR5KCNH2SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-B1 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | EP | disclosed |
| CN-101405284-A | Pyrimidine, quinazoline, pteridine and derivatives | HOFFMANN LA ROCHE (CH) | 2009-04-08 | — | — | CN | disclosed |