Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057643 | 0.84 | SLC6A2 (0.64) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL4940308 | 0.83 | SLC6A2 (0.62) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4063112 | 0.83 | SLC6A2 (0.44) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4055598 | 0.82 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4059632 | 0.82 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4057117 | 0.79 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4055314 | 0.76 | SLC6A2 (0.44) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL4540522 | 0.71 | SLC6A2 (0.42) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4064050 | 0.70 | SLC6A2 (0.59) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4062370 | 0.69 | SLC6A2 (0.60) | SLC6A2SLC6A3SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061776-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | Wyeth a Corporation of the State of Delaware (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008073459-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |