Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.45 |
| ▸ | CDC25B | P30305 | 7/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Netoglitazone SCHEMBL29355957 | 0.89 | FFAR1 (0.55) | PTPN1PARP15PARP10PTPN2CDC25B | |
| Netoglitazone SCHEMBL20125596 | 0.89 | FFAR1 (0.55) | PTPN1PARP15PARP10PTPN2CDC25B | |
| Netoglitazone SCHEMBL29355960 | 0.89 | FFAR1 (0.55) | PTPN1PARP15PARP10PTPN2CDC25B | |
| Netoglitazone SCHEMBL142658 | 0.89 | FFAR1 (0.55) | PTPN1PARP15PARP10PTPN2CDC25B | |
| Netoglitazone SCHEMBL29361540 | 0.89 | FFAR1 (0.55) | PTPN1PARP15PARP10PTPN2CDC25B | |
| Netoglitazone SCHEMBL20125595 | 0.89 | FFAR1 (0.55) | PTPN1PARP15PARP10PTPN2CDC25B | |
| Netoglitazone SCHEMBL29434827 | 0.89 | FFAR1 (0.55) | PTPN1PARP15PARP10PTPN2CDC25B | |
| Netoglitazone SCHEMBL8877880 | 0.88 | FFAR1 (0.54) | PTPN1PARP15PARP10PTPN2CDC25B | |
| SCHEMBL10281143 | 0.80 | PTPN1 (0.48) | MAOBPTPN1PARP15PARP10PTPN2 | |
| SCHEMBL7514721 | 0.79 | PTPN1 (0.52) | MAOBPTPN1PARP15PARP10PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009234930-A | 2-IMINO-4-THIAZOLIDINONE DERIVATIVE AND METHOD FOR PRODUCING 2,4-THIAZOLIDINEDIONE DERIVATIVE | OHARA YAKUHIN KOGYO KK | 2009-10-15 | — | — | JP | disclosed |