SCHEMBL4240810

SCHEMBL4240810

COC(=O)c1cccc(OCc2nc3ccc(Oc4cccc(F)c4)cc3n2C)c1

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3487899 0.99 PPARG (0.81) PPARG
SCHEMBL3488043 0.95 PPARG (0.83) PPARG
SCHEMBL3487287 0.94 PPARG (0.82) PPARG
SCHEMBL3487529 0.94 PPARG (0.75) PPARG
SCHEMBL3487509 0.93 PPARG (0.76) PPARG
SCHEMBL3486641 0.92 PPARG (0.84) PPARG
SCHEMBL3487140 0.92 PPARG (0.83) PPARG
SCHEMBL3487357 0.91 PPARG (0.84) PPARG
Hydrochloric Acid SCHEMBL3487401 0.90 PPARG (0.83) PPARG
SCHEMBL3487795 0.90 PPARG (0.84) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2138484-B1 FUSED BICYCLIC HETEROARYL DERIVATIVES DAIICHI SANKYO CO LTD (JP) 2015-08-26 EP disclosed
EP-2138484-A1 FUSED BICYCLIC HETEROARYL DERIVATIVES Daiichi Sankyo Company, Limited (JP) 2009-12-30 EP disclosed