SCHEMBL4240975

SCHEMBL4240975

O=C1N=CC(I)=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16497484 0.69
SCHEMBL8623934 0.65
SCHEMBL1693134 0.65
SCHEMBL6235779 0.64
SCHEMBL2160930 0.61
SCHEMBL5604658 0.61
SCHEMBL27388395 0.61
SCHEMBL27500383 0.61
SCHEMBL3365887 0.60
SCHEMBL2063239 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090088571-A1 Synthesis of 6,7-Dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid amides BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-04-02 US disclosed
US-7470795-B2 Synthesis of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid amides BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2008-12-30 US disclosed
EP-1979309-A2 PROCESS FOR THE PREPARATION OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-A]IMIDAZOLE-3-SULFONIC ACID AMIDES AND INTERMEDIATES USED THEREIN Boehringer Ingelheim International GmbH (DE) 2008-10-15 EP disclosed
CN-101027304-A Synthesis of 6, 7-dihydro-5H-imidazo [1, 2-A ] imidazole-3-sulfonamides BOEHRINGER INGELHEIM INT (DE) 2007-08-29 CN disclosed
WO-2007084882-A2 PROCESS FOR THE PREPARATION OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-A]IMIDAZOLE-3-SULFONIC ACID AMIDES AND INTERMEDIATES USED THEREIN BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-07-26 WO disclosed
US-20070173517-A1 Synthesis of 6,7-Dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid amides WIRTH THOMAS 2007-07-26 US disclosed
EP-1776367-A1 SYNTHESIS OF 6,7-DIHYDRO-5H-IMIDAZOÝ1,2-A¨IMIDAZOLE-3-SULFONIC ACID AMIDES Boehringer Ingelheim International GmbH (DE) 2007-04-25 EP disclosed
WO-2006014828-A1 SYNTHESIS OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-A]IMIDAZOLE-3-SULFONIC ACID AMIDES BOEHRINGER INGELHEIM INTERNATIONAL, GMBH (DE) 2006-02-09 WO disclosed
US-20060025447-A1 Synthesis of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid amides BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2006-02-02 US disclosed