Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 18/20 | 0.80 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241334 | 1.00 | CHEK1 (0.80) | CHEK1KDRFLT3AURKB | |
| SCHEMBL4021457 | 0.93 | CHEK1 (0.82) | CHEK1 | |
| SCHEMBL4021467 | 0.93 | CHEK1 (0.82) | CHEK1 | |
| SCHEMBL4016657 | 0.92 | CHEK1 (0.84) | CHEK1 | |
| SCHEMBL4016660 | 0.92 | CHEK1 (0.84) | CHEK1 | |
| SCHEMBL4015290 | 0.89 | CHEK1 (1.00) | CHEK1 | |
| SCHEMBL4015294 | 0.89 | CHEK1 (1.00) | CHEK1 | |
| SCHEMBL4016918 | 0.85 | CHEK1 (1.00) | CHEK1 | |
| SCHEMBL4016913 | 0.85 | CHEK1 (1.00) | CHEK1 | |
| SCHEMBL4013881 | 0.83 | CHEK1 (0.75) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163494-A1 | PROTEIN KINASE INHIBITORS | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163494-A1 | PROTEIN KINASE INHIBITORS | BRAF, MAP3K20, SELENOI | CHEK1 120/4885KDR 2756/4885FLT3 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.