SCHEMBL4241644

SCHEMBL4241644

C=CC(=CC)CCCCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.46
ALDH1A1 P00352 3/20 0.46
CES2 O00748 3/20 0.44
CES1 P23141 3/20 0.44
FAAH O00519 1/20 0.44
GPR84 Q9NQS5 7/20 0.42
PPARG P37231 7/20 0.42
PPARD Q03181 7/20 0.42
PPARA Q07869 7/20 0.42
HDAC11 Q96DB2 5/20 0.42
PTPN1 P18031 3/20 0.42
TLR2 O60603 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
FABP4 P15090 2/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
SLC22A8 Q8TCC7 1/20 0.42
MEN1 O00255 1/20 0.42
ESR1 P03372 1/20 0.42
ALOX15 P16050 1/20 0.42
PDE4A P27815 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8706420 0.97 TSHR (0.42) TSHRALDH1A1CES2CES1FAAH
SCHEMBL3637885 0.90
SCHEMBL320998 0.90
SCHEMBL29284509 0.84 TSHR (0.41) TSHRALDH1A1CES2CES1FAAH
SCHEMBL26084994 0.84 TSHR (0.41) TSHRALDH1A1CES2CES1FAAH
SCHEMBL26084995 0.84 TSHR (0.41) TSHRALDH1A1CES2CES1FAAH
SCHEMBL29284448 0.82 TSHR (0.48) TSHRFAAHPPARGPPARDPPARA
SCHEMBL29284385 0.82 TSHR (0.43) TSHRALDH1A1CES2CES1FAAH
SCHEMBL29284373 0.82 TSHR (0.43) TSHRALDH1A1CES2CES1FAAH
SCHEMBL8704427 0.81 TSHR (0.46) TSHRALDH1A1CES2CES1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1553463-B1 Charging unit and image forming apparatus incorporating the unit RICOH CO LTD (JP) 2013-09-18 EP disclosed
US-7596344-B2 Charging unit and image forming apparatus incorporating the unit RICOH COMPANY, LTD. (JP) 2009-09-29 US disclosed
US-20080107452-A1 CHARGING UNIT AND IMAGE FORMING APPARATUS INCORPORATING THE UNIT KOSUGE AKIO 2008-05-08 US disclosed
US-7340200-B2 Charging unit and image forming apparatus incorporating the unit RICOH COMPANY, LTD. (JP) 2008-03-04 US disclosed
US-20050175374-A1 Charging unit and image forming apparatus incorporating the unit RICOH COMPANY, LTD. (JP) 2005-08-11 US disclosed
EP-1553463-A2 Charging unit and image forming apparatus incorporating the unit Ricoh Company (JP) 2005-07-13 EP disclosed
US-6110880-A BLOCKS OF ETHYLENE AND BLOCKS OF ETHYLENE AND AT LEAST ONE OTHER ALPHA-OLEFIN; BLOCK COPOLYMER HAS AN AVERAGE ETHYLENE CONTENT OF 60 TO 80 WEIGHT %; IMPROVED BALANCE OF THICKENING EFFICIENCY AND SHEAR STABILITY; USE IN LUBRICATING OILS EXXON CHEMICAL PATENTS INC (US) 2000-08-29 US disclosed
US-4545939-A REACTING MIXTURE OF LOWER ALKYL ESTER OF UNSATURATED FATTY ACID AND LOWER ALKYL ESTER OF SATURATED FATTY ACID LION CORPORATION (JP) 1985-10-08 US disclosed