Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | AURKA | O14965 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | MAPK8 | P45983 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.56 |
| ▸ | CDC7 | O00311 | 1/20 | 0.55 |
| ▸ | FABP4 | P15090 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395312 | 1.00 | MEN1 (0.63) | MEN1KMT2AMAPK10GFERAURKA | |
| SCHEMBL11665185 | 0.86 | MEN1 (0.58) | MEN1KMT2AMAPK10GFERAURKA | |
| SCHEMBL10837028 | 0.85 | JAK2 (0.63) | MEN1KMT2AMAPK10GFERAURKA | |
| SCHEMBL15286528 | 0.84 | KDM4C (0.56) | MEN1KMT2AMAPK10GFERKDM4E | |
| SCHEMBL11471869 | 0.83 | GRIK1 (0.53) | MEN1KMT2AMAPK10GFERAURKA | |
| SCHEMBL11482055 | 0.83 | AKR1C3 (0.51) | MEN1KMT2AMAPK10GFERAURKA | |
| SCHEMBL4191649 | 0.82 | AURKA (0.71) | AURKAKDM4EL3MBTL1MAPK8ALDH1A1 | |
| SCHEMBL29394920 | 0.82 | KDM4E (0.60) | MEN1KMT2AMAPK10GFERAURKA | |
| Water SCHEMBL11463957 | 0.82 | AKR1C3 (0.50) | MEN1KMT2AMAPK10GFERAURKA | |
| SCHEMBL11465530 | 0.79 | JAK2 (0.49) | MEN1KMT2AMAPK10GFERAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101302229-A | Tetraheteropoly rare earth organic complex and preparation thereof | UNIV BEIJING CHEMICAL (CN) | 2008-11-12 | — | — | CN | claimed |
| EP-2100881-A1 | Pyrimidyl- or pyridinylaminobenzoic acid derivatives | Laboratorios Almirall, S.A. (ES) | 2009-09-16 | — | — | EP | disclosed |
| CN-101302229-A | Tetraheteropoly rare earth organic complex and preparation thereof | UNIV BEIJING CHEMICAL (CN) | 2008-11-12 | — | — | CN | disclosed |
| EP-0114734-B1 | PYRIDINYLMETHYLAMINO-ARYLIC ACIDS | THE UPJOHN COMPANY (US) | 1987-05-13 | — | — | EP | disclosed |
| EP-0098951-A3 | AMINOBENZAMIDE DERIVATIVES AND PREPARATION THEREOF | STERLING DRUG INC. (US) | 1985-01-23 | — | — | EP | disclosed |
| US-4486593-A | 2-,3-, or 4-Pyridinylmethylamino arylic acids as thromboxane A2 synthetase and 5-lipoxygenase inhibitors | THE UPJOHN COMPANY (US) | 1984-12-04 | — | — | US | disclosed |
| EP-0114734-A2 | Pyridinylmethylamino-arylic acids | THE UPJOHN COMPANY (US) | 1984-08-01 | — | — | EP | disclosed |
| EP-0100158-A2 | (3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters | THE UPJOHN COMPANY (US) | 1984-02-08 | — | — | EP | disclosed |
| US-4241068-A | ANTIALLERGENS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-12-23 | — | — | US | disclosed |