Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.76 |
| ▸ | PPARA | Q07869 | 8/20 | 0.73 |
| ▸ | PPARD | Q03181 | 8/20 | 0.73 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.71 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4240882 | 0.92 | PPARG (0.72) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL4231903 | 0.89 | NR1H2 (0.65) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL5335361 | 0.89 | PPARA (0.72) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL4232794 | 0.89 | PPARG (0.90) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL5009211 | 0.89 | PPARG (0.84) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL5009392 | 0.89 | PPARG (0.79) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL4229806 | 0.88 | PPARG (0.73) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL4242174 | 0.88 | PPARG (0.77) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL4239688 | 0.87 | PPARG (0.83) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL5008732 | 0.86 | PPARG (1.00) | PPARGPPARAPPARDNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689389-A4 | INDOLE COMPOUNDS | NAT HEALTH RESEARCH INSTITUTES (TW) | 2009-06-17 | — | — | EP | disclosed |
| US-7449478-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-11-11 | — | — | US | disclosed |
| US-7449478-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-11-11 | — | — | US | disclosed |
| EP-1689389-A2 | INDOLE COMPOUNDS | National Health Research Institutes (TW) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005056522-A2 | INDOLE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-06-23 | — | — | WO | disclosed |
| US-20050124675-A1 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124675-A1 | Indole compounds | PPARG, PPARD, PPARA | PPARG 1/4885PPARA 3/4885PPARD 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.