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SCHEMBL4244285

SCHEMBL4244285

O=S1(=O)N(CC[C@@H](O)CNC2CC2)c2ccccc2N1c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 20/20 1.00
▸ SLC6A3 Q01959 11/20 0.71
▸ KCNH2 Q12809 2/20 0.71
▸ SLC6A4 P31645 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3613295 1.00 SLC6A2 (1.00) SLC6A2SLC6A3KCNH2SLC6A4
SCHEMBL4064382 1.00 SLC6A2 (1.00) SLC6A2SLC6A3KCNH2SLC6A4
SCHEMBL3613297 0.87 SLC6A2 (0.78) SLC6A2SLC6A3KCNH2SLC6A4
SCHEMBL4064387 0.87 SLC6A2 (0.78) SLC6A2SLC6A3KCNH2SLC6A4
SCHEMBL4061277 0.87 SLC6A2 (0.77) SLC6A2SLC6A3KCNH2SLC6A4
SCHEMBL3606290 0.87 SLC6A2 (0.77) SLC6A2SLC6A3KCNH2SLC6A4
SCHEMBL3606546 0.87 SLC6A2 (0.77) SLC6A2SLC6A3KCNH2SLC6A4
SCHEMBL14088534 0.86 SLC6A2 (0.76) SLC6A2SLC6A3KCNH2SLC6A4
SCHEMBL3612085 0.86 SLC6A2 (0.75) SLC6A2SLC6A3KCNH2SLC6A4
SCHEMBL4060981 0.83 SLC6A2 (1.00) SLC6A2SLC6A3KCNH2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2061776-A1 ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE Wyeth a Corporation of the State of Delaware (US) 2009-05-27 — — EP disclosed
WO-2008073459-A1 ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE WYETH (US) 2008-06-19 — — WO disclosed