⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565556 | 0.88 | — | — | |
| SCHEMBL465769 | 0.87 | — | — | |
| SCHEMBL919637 | 0.87 | — | — | |
| SCHEMBL11259580 | 0.84 | EPHX1 (0.39) | — | |
| SCHEMBL2409118 | 0.80 | — | — | |
| SCHEMBL8790273 | 0.78 | TSHR (0.38) | — | |
| SCHEMBL920032 | 0.73 | — | — | |
| SCHEMBL6036729 | 0.71 | — | — | |
| SCHEMBL8789499 | 0.68 | CNR2 (0.34) | — | |
| SCHEMBL6221172 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 746 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4293016-A1 | QUINAZOLINE-BASED COMPOUND, COMPOSITION, AND APPLICATION OF QUINAZOLINE-BASED COMPOUND | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2023-12-20 | — | — | EP | claimed |
| WO-2023147513-A2 | COMPOSITIONS OF AUTOPHAGY MODULATING AGENTS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2023-08-03 | — | — | WO | claimed |
| CN-114381748-B | Hydroboration reaction method for electrochemically catalyzing aldehyde ketone | 南京林业大学 | 2023-03-10 | — | — | CN | claimed |
| CN-115109036-A | Quinazoline compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-114381748-A | Hydroboration reaction method for electrochemically catalyzing aldehyde ketone | 南京林业大学 | 2022-04-22 | — | — | CN | claimed |
| CN-112266327-A | Method for synthesizing beta-hydroxycarbonyl compound by catalyzing asymmetric Aldol reaction in aqueous phase | 昆明理工大学 | 2021-01-26 | — | — | CN | claimed |
| US-9394297-B2 | Amides as pim inhibitors | AMGEN INC. (US) | 2016-07-19 | — | — | US | claimed |
| US-20150329538-A1 | AMIDES AS PIM INHIBITORS | AMGEN INC. (US) | 2015-11-19 | — | — | US | claimed |
| EP-2556046-B1 | PROCESS FOR PREPARING UNSYMMETRICAL SECONDARY TERT-BUTYLAMINES IN THE LIQUID PHASE | BASF SE (DE) | 2014-10-08 | — | — | EP | claimed |
| US-8846898-B2 | Phosphinoamidite carboxylates and analogs thereof in the synthesis of oligonucleotide having reduced internucleotide charge | Lieure Cornu LLC (US) | 2014-09-30 | — | — | US | claimed |
| US-5236999-A | OXOACETALS OF POLYVINYL ALCOHOLS, PROCESSES FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-17 | — | — | US | claimed |
| US-5218103-A | Nucleoside thiophosphoramidites | UNIVERSITY PATENTS, INC. (US) | 1993-06-08 | — | — | US | claimed |
| EP-0378615-A4 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | — | 1992-04-08 | — | — | EP | claimed |
| WO-1991004983-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | UNIVERSITY PATENTS, INC. (US) | 1991-04-18 | — | — | WO | claimed |
| US-4958033-A | ACETYLENIC, CARBONYL COMPOUND OR OXIRANE, PROPARGYL HALIDE, MAGNESIUM, ZINC OR ITS HALIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-09-18 | — | — | US | claimed |
| EP-0378615-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | COMPETITIVE TECHNOLOGIES INC. (US) | 1990-07-25 | — | — | EP | claimed |
| WO-1989011486-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | UNIVERSITY PATENTS, INC. (US) | 1989-11-30 | — | — | WO | claimed |
| US-4582903-A | Synthesis of unsaturated hydantoins with an inexpensive catalyst | STAUFFER CHEMICAL COMPANY (US) | 1986-04-15 | — | — | US | claimed |
| US-4212825-A | Aldol condensation and hydrogenation process using a catalyst of nickel and cobalt together with zinc oxide and another metal of groups VIII, IIb, IIIa, IVa and Va of the periodic table | BASF AKTIENGESELLSCHAFT (DE) | 1980-07-15 | — | — | US | claimed |
| US-4181810-A | FROM THE 2-SUBSTITUTED ETHANAL AND FORMALDEHYDE USING AN ACID ION EXCHANGER; HYDROGENATION OF REACTION PRODUCT | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-01 | — | — | US | claimed |