Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTAP | Q13126 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 7/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4244685 | 1.00 | MTAP (0.38) | MTAPPNPBCHEACHEIP6K1 | |
| SCHEMBL4736624 | 1.00 | MTAP (0.38) | MTAPPNPBCHEACHEIP6K1 | |
| SCHEMBL12715788 | 0.89 | USP2 (0.35) | MTAPPNPIP6K1HPRT1 | |
| SCHEMBL4736639 | 0.83 | MTAP (0.39) | MTAPBCHEACHE | |
| SCHEMBL4736611 | 0.79 | MTAP (0.33) | MTAP | |
| SCHEMBL12715836 | 0.75 | USP2 (0.35) | MTAP | |
| SCHEMBL12715787 | 0.70 | USP2 (0.31) | MTAP | |
| SCHEMBL13801674 | 0.70 | HPRT1 (0.42) | BCHEACHEIP6K1CTSVCTSL | |
| SCHEMBL5351452 | 0.66 | GBA1 (0.42) | MTAPBCHEACHECTSLCTSB | |
| SCHEMBL13801675 | 0.66 | MTAP (0.35) | MTAPPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553839-B2 | 5h-pyrrolo[3,2-D] pyrimidine inhibitors of nucleoside phosphorylases and nucleosidases | INDUSTRIAL RESEARCH LIMITED (NZ) | 2009-06-30 | — | — | US | disclosed |
| US-20060160765-A1 | Inhibitors of nucleoside phosphorylases and nucleosidases | BIOCRYST PHARMACEUTICALS, INC. | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160765-A1 | Inhibitors of nucleoside phosphorylases and nucleosidases | PNP, MTAP, TYMP | MTAP 2/4885PNP 1/4885BCHE 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.