Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.37 |
| ▸ | DRD2 | P14416 | 7/20 | 0.37 |
| ▸ | RXRA | P19793 | 3/20 | 0.31 |
| ▸ | RXRB | P28702 | 3/20 | 0.31 |
| ▸ | RXRG | P48443 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140159 | 0.72 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL29196629 | 0.64 | — | — | |
| SCHEMBL20571402 | 0.60 | GAA (0.48) | — | |
| SCHEMBL20571985 | 0.60 | MEN1 (0.38) | HTR2A | |
| SCHEMBL20571349 | 0.59 | HTT (0.30) | — | |
| SCHEMBL20571152 | 0.59 | KDM4E (0.36) | — | |
| SCHEMBL23722449 | 0.59 | ITGAV (0.33) | — | |
| SCHEMBL20141262 | 0.59 | FGFR4 (0.39) | — | |
| Ammonia Solution, Strong SCHEMBL28819769 | 0.59 | PIK3CD (0.40) | — | |
| Methacrylic Acid SCHEMBL23648352 | 0.59 | NPSR1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049490-A1 | N-(BENZOYL)-O- [2- (PYRIDIN- 2 -YLAMINO) ETHYL]-L-TYROSINE DERIVATIVES AND RELATED COMPOUNDS AS A5B1 ANTAGONISTS FOR THE TREATMENT OF SOLID TUMORS | Astra Zeneca AB (SE) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007141473-A1 | N-(BENZOYL)-O- [2- (PYRIDIN- 2 -YLAMINO) ETHYL] -L-TYROSINE DERIVATIVES AND RELATED COMPOUNDS AS A5B1 ANTAGONISTS FOR THE TREATMENT OF SOLID TUMORS | ASTRAZENECA AB (SE) | 2007-12-13 | — | — | WO | disclosed |