Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.59 |
| ▸ | TLR8 | Q9NR97 | 14/20 | 0.59 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4252345 | 0.87 | TLR7 (0.55) | TLR7TLR8NUDT1 | |
| SCHEMBL4241225 | 0.86 | TLR7 (0.52) | TLR7TLR8NUDT1 | |
| SCHEMBL4248169 | 0.85 | TLR7 (0.41) | TLR7TLR8NUDT1 | |
| SCHEMBL1486698 | 0.83 | TLR7 (0.81) | TLR7TLR8NUDT1 | |
| SCHEMBL1486706 | 0.81 | TLR7 (0.61) | TLR7TLR8NUDT1 | |
| SCHEMBL1486783 | 0.81 | TLR7 (0.57) | TLR7TLR8NUDT1 | |
| SCHEMBL4246425 | 0.81 | TLR7 (0.47) | TLR7TLR8NUDT1 | |
| SCHEMBL1486686 | 0.81 | TLR7 (0.61) | TLR7TLR8NUDT1 | |
| SCHEMBL1486429 | 0.80 | TLR7 (0.79) | TLR7TLR8NUDT1 | |
| SCHEMBL24495895 | 0.80 | TLR7 (0.68) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658076-A4 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2009-02-25 | — | — | EP | disclosed |
| EP-1658076-A1 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005020999-A1 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-03-10 | — | — | WO | disclosed |