SCHEMBL424692

SCHEMBL424692

C=CC(=O)NC(CC)N(C)C

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
ALDH1A1 P00352 3/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
ACACB O00763 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5487753 0.98 TSHR (0.47) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL7629624 0.91 TSHR (0.41) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL10628352 0.88 TSHR (0.39) TSHRZDHHC20ZDHHC2
SCHEMBL902178 0.86 TSHR (0.37) TSHRZDHHC20ZDHHC2
SCHEMBL7712238 0.85 TSHR (0.45) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL3285064 0.82 TSHR (0.47) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL8034283 0.82 TSHR (0.34) TSHR
SCHEMBL7630925 0.82 TSHR (0.34) TSHR
SCHEMBL10423873 0.81 TSHR (0.45) TSHRALDH1A1MAPK1TDP1ZDHHC20
Hydrochloric Acid SCHEMBL29008141 0.81 TSHR (0.45) TSHRALDH1A1MAPK1TDP1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1670 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120018945-A Three-dimensional printing method for fiber composite material MOI复合材料有限责任公司 2025-05-16 CN claimed
CN-117757452-A Bulk-expansion particles with slow expansion property and preparation method thereof 中国石油天然气股份有限公司 2024-03-26 CN claimed
CN-117756980-A Preparation method of cross-linking agent for acrylamide polymer type gel 中国石油大学(华东) 2024-03-26 CN claimed
CN-117568328-A Immobilized enzyme and preparation method thereof 华东理工大学 2024-02-20 CN claimed
US-11828915-B2 Methods and compositions for improved comfort contact lens UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-11-28 US claimed
CN-116444737-B Cationic acrylic resin retanning agent and preparation method thereof 四川大学 2023-10-10 CN claimed
CN-116444737-A Cationic acrylic resin retanning agent and preparation method thereof 四川大学 2023-07-18 CN claimed
CN-116003679-A Method for efficiently preparing polyelectrolyte particles by ultraviolet irradiation 华东理工大学 2023-04-25 CN claimed
US-20220413189-A1 METHODS AND COMPOSITIONS FOR IMPROVED COMFORT CONTACT LENS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2022-12-29 US claimed
CN-115461436-A Surfactants for cleaning products 艾德凡斯化学公司 2022-12-09 CN claimed
CN-1334830-A Hydrophilic ampholytic polymer GOODRICH CO B F (US) 2002-02-06 CN claimed
EP-1148895-A1 THERMO-REVERSIBLE POLYMER FOR INTRALUMENAL IMPLANT The Regents of the University of California (US) 2001-10-31 EP claimed
EP-0859796-B1 AQUEOUS COMPOSITIONS THICKENED WITH ACRYLATE-BASED POLYMERIC RHEOLOGY MODIFIERS NAT STARCH CHEM CORP (US) 2000-11-02 EP claimed
WO-2000045868-A1 THERMO-REVERSIBLE POLYMER FOR INTRALUMENAL IMPLANT THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-08-10 WO claimed
US-5349023-A Vinyl alcohol copolymer having terminal amino group KURARAY CO., LTD. (JP) 1994-09-20 US claimed
US-4650596-A OIL ADDITIVES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1987-03-17 US claimed
EP-0040124-B1 HYDROPHILIC COPOLYMERS BASED ON N-TRIS(HYDROXY-METHYL)METHYLACRYL AMIDE, PROCESS FOR THEIR PREPARATION, AQUEOUS GEL OF THESE COPOLYMERS AND THEIR USE AS ION EXCHANGERS PHARMUKA LABORATOIRES (FR) 1985-03-27 EP claimed
EP-0040124-A1 Hydrophilic copolymers based on N-tris(hydroxy-methyl)methylacryl amide, process for their preparation, aqueous gel of these copolymers and their use as ion exchangers PHARMUKA LABORATOIRES (FR) 1981-11-18 EP claimed
US-4115260-A ACRYLIC ANION EXCHANGE RESINS ROHM AND HAAS COMPANY (US) 1978-09-19 US claimed
US-4082551-A GOOD ADHESION AND BLOCKING POSITIVE CHARGED PARTICLES EASTMAN KODAK COMPANY (US) 1978-04-04 US claimed