SCHEMBL4247941

SCHEMBL4247941

CCCCCCCCCCOP(=O)(O)Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 3/20 0.48
KMT2A Q03164 3/20 0.47
GAA P10253 3/20 0.47
MEN1 O00255 2/20 0.47
LPAR3 Q9UBY5 6/20 0.45
LPAR2 Q9HBW0 5/20 0.45
LPAR1 Q92633 2/20 0.45
NR1I2 O75469 1/20 0.42
ALDH1A1 P00352 2/20 0.39
TSHR P16473 2/20 0.39
USP2 O75604 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
BLM P54132 1/20 0.39
ATM Q13315 1/20 0.39
HIF1A Q16665 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL915217 1.00 HMGCR (0.48) HMGCRKMT2AGAAMEN1LPAR3
SCHEMBL8869012 1.00 HMGCR (0.48) HMGCRKMT2AGAAMEN1LPAR3
SCHEMBL28541822 1.00 HMGCR (0.48) HMGCRKMT2AGAAMEN1LPAR3
SCHEMBL28387496 1.00 HMGCR (0.48) HMGCRKMT2AGAAMEN1LPAR3
SCHEMBL809384 1.00 HMGCR (0.48) HMGCRKMT2AGAAMEN1LPAR3
SCHEMBL8106694 0.99 HMGCR (0.47) HMGCRKMT2AGAAMEN1LPAR3
SCHEMBL10701901 0.94 HMGCR (0.50) HMGCRKMT2AGAAMEN1NR1I2
SCHEMBL7676495 0.93 HMGCR (0.49) HMGCRKMT2AGAAMEN1NR1I2
SCHEMBL11289344 0.92 HMGCR (0.41) HMGCRKMT2AGAAMEN1LPAR3
SCHEMBL20139162 0.92 HMGCR (0.41) HMGCRKMT2AGAAMEN1LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024062086-A1 FLAME RETARDANT POLYCARBONATE FORMULATIONS TRINSEO EUROPE GMBH (CH) 2024-03-28 WO disclosed
EP-4342948-A1 FLAME RETARDANT POLYCARBONATE FORMULATIONS Trinseo Europe GmbH (CH) 2024-03-27 EP disclosed
WO-2024013214-A1 POLYCARBONATES WITH HIGH POST-CONSUMER RECYCLE CONTENT TRINSEO EUROPE GMBH (CH) 2024-01-18 WO disclosed
WO-2024013165-A1 RECYCLING METHOD FOR POST-CONSUMER AND/OR POST-INDUSTRIAL IMPACT MODIFIED POLYMERS TRINSEO EUROPE GMBH (CH) 2024-01-18 WO disclosed
EP-4306594-A1 POLYCARBONATES WITH HIGH POST-CONSUMER RECYCLE CONTENT Trinseo Europe GmbH (CH) 2024-01-17 EP disclosed
EP-4306587-A1 RECYCLING METHOD FOR POST-CONSUMER AND/OR POST-INDUSTRIAL IMPACT MODIFIED POLYMERS Trinseo Europe GmbH (CH) 2024-01-17 EP disclosed
WO-2023156433-A1 EXTREMELY LOW ODOR VINYLIDENE SUBSTITUTED AROMATIC POLYMER CONTAINING COMPOSITION TRINSEO EUROPE GMBH (CH) 2023-08-24 WO disclosed
EP-4230689-A1 EXTREMELY LOW ODOR VINYLIDENE SUBSTITUTED AROMATIC POLYMER CONTAINING COMPOSITION Trinseo Europe GmbH (CH) 2023-08-23 EP disclosed
WO-2009092494-A1 UV-ABSORBENT COORDINATION POLYMER BASF SE (DE) 2009-07-30 WO disclosed
EP-1926770-A1 COLOR FAST POLYURETHANES Ciba Holding Inc. (CH) 2008-06-04 EP disclosed
WO-2007039434-A1 COLOR FAST POLYURETHANES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-04-12 WO disclosed
EP-0354185-A2 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1990-02-07 EP disclosed