SCHEMBL424807

SCHEMBL424807

CC(C)(C)NN(C(=O)O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
MEN1 O00255 3/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
ALDH1A1 P00352 5/20 0.42
TDP1 Q9NUW8 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
RAB9A P51151 1/20 0.42
LMNA P02545 2/20 0.41
HTT P42858 2/20 0.41
NPSR1 Q6W5P4 1/20 0.40
GLA P06280 1/20 0.38
TSHR P16473 1/20 0.38
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3398124 0.75 POLB (0.51) KMT2ASMN1; SMN2MEN1CYP3A4CYP2C9
SCHEMBL5622596 0.74 TDP1 (0.52) KMT2ASMN1; SMN2MEN1ALDH1A1TDP1
SCHEMBL5624200 0.72 TDP1 (0.46) KMT2ASMN1; SMN2MEN1ALDH1A1TDP1
SCHEMBL3080983 0.71 SMN1; SMN2 (0.69) KMT2ASMN1; SMN2MEN1CYP3A4ALDH1A1
SCHEMBL18491121 0.71 TDP1 (0.44) KMT2ASMN1; SMN2MEN1ALDH1A1TDP1
SCHEMBL15317111 0.71 NR3C2 (0.44) KMT2ASMN1; SMN2ALDH1A1TDP1L3MBTL1
SCHEMBL27997106 0.69 TDP1 (0.47) KMT2ASMN1; SMN2MEN1CYP3A4CYP2C19
SCHEMBL3323146 0.69 AKT1 (0.50) KMT2AMEN1ALDH1A1L3MBTL1RAB9A
SCHEMBL10565579 0.68 AKT1 (0.49) KMT2ASMN1; SMN2MEN1ALDH1A1TDP1
SCHEMBL7034982 0.68 KMT2A (0.47) KMT2ASMN1; SMN2MEN1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7115676-B2 Adhesive compositions for bonding passive substrates HENKEL CORPORATION (US) 2006-10-03 US claimed
US-20030217808-A1 Adhesive compositions for bonding passive substrates Henkel IP & Holding GmbH (DE) 2003-11-27 US claimed
EP-1285037-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS Henkel Loctite Corporation (US) 2003-02-26 EP claimed
WO-2001088050-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS HENKEL LOCTITE CORPORATION (US) 2001-11-22 WO claimed
CN-113773234-A Method for oxidizing hydrazine compound into azo compound 台州学院 2021-12-10 CN disclosed
US-20120018088-A1 METHOD FOR CONNECTING ELECTRODES AND BONDING COMPOSITION USED THEREFOR HENKEL CORPORATION (US) 2012-01-26 US disclosed
US-7115676-B2 Adhesive compositions for bonding passive substrates HENKEL CORPORATION (US) 2006-10-03 US disclosed
US-20030217808-A1 Adhesive compositions for bonding passive substrates Henkel IP & Holding GmbH (DE) 2003-11-27 US disclosed
EP-1285037-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS Henkel Loctite Corporation (US) 2003-02-26 EP disclosed
WO-2001088050-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS HENKEL LOCTITE CORPORATION (US) 2001-11-22 WO disclosed
US-4321349-A Accelerator for curable compositions LOCTITE CORPORATION (US) 1982-03-23 US disclosed
US-4287330-A Accelerator for curable compositions LOCTITE CORPORATION (US) 1981-09-01 US disclosed
US-4180640-A HYDRAZIDE DERIVATIVES LOCTITE CORPORATION (US) 1979-12-25 US disclosed