⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96488 | 0.87 | — | — | |
| SCHEMBL1699318 | 0.84 | — | — | |
| SCHEMBL8500348 | 0.84 | — | — | |
| SCHEMBL8500220 | 0.84 | — | — | |
| SCHEMBL2541524 | 0.84 | — | — | |
| SCHEMBL7857443 | 0.84 | — | — | |
| SCHEMBL8498984 | 0.84 | — | — | |
| SCHEMBL8497937 | 0.84 | — | — | |
| SCHEMBL2094653 | 0.84 | — | — | |
| SCHEMBL8500174 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4633 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348421-A1 | 5-HT2A RECEPTOR INHIBITOR OR INVERSE AGONIST, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | LUYE INNOMIND PHARMA SHIJIAZHUANG CO., LTD. (CN) | 2023-11-02 | — | — | US | claimed |
| CN-114728933-B | 5-HT 2A Receptor inhibitor or inverse agonist, preparation method and application thereof | 山东绿叶制药有限公司 | 2023-06-16 | — | — | CN | claimed |
| EP-4186893-A1 | 5-HT2A RECEPTOR INHIBITOR OR INVERSE AGONIST, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Geneora Pharma (Shijiazhuang) Co., Ltd. (CN) | 2023-05-31 | — | — | EP | claimed |
| CN-114539269-B | Nitrogen-containing macrocyclic compound, preparation method and application thereof | 上海医药工业研究院有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-115894317-A | Micromolecular compound with naphthylthiophenol ether structure and application thereof | 杭州天玑济世生物科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115894404-A | Micromolecular compound with naphthylamine structure and application thereof | 杭州天玑济世生物科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| WO-2023045910-A1 | SMALL-MOLECULE COMPOUND HAVING NAPHTHOL ETHER STRUCTURE, AND USE THEREOF | 杭州天玑济世生物科技有限公司 | 2023-03-30 | — | — | WO | claimed |
| CN-114728933-A | 5-HT2AReceptor inhibitor or inverse agonist, preparation method and application thereof | 山东绿叶制药有限公司 | 2022-07-08 | — | — | CN | claimed |
| CN-114649584-A | Electrolyte containing aromatic ring-type sulfur-based boron trifluoride salt and preparation method and application thereof | 北京卫蓝新能源科技有限公司 | 2022-06-21 | — | — | CN | claimed |
| US-11345693-B2 | Compounds, salts thereof and methods for treatment of diseases | ACADIA PHARMACEUTICALS INC. (US) | 2022-05-31 | — | — | US | claimed |
| EP-1575943-A1 | 3-CYANO-QUINOLINE DERIVATIVES | AstraZeneca AB (SE) | 2005-09-21 | — | — | EP | claimed |
| EP-1521751-A1 | SUBSTITUTED 3-CYANOQUINOLINES AS MEK INHIBITORS | Astrazeneca AB (SE) | 2005-04-13 | — | — | EP | claimed |
| US-20040164272-A1 | Dichoric mixture | ROLIC AG (CH) | 2004-08-26 | — | — | US | claimed |
| WO-2004041811-A1 | 3-CYANO-QUINOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-05-21 | — | — | WO | claimed |
| EP-1385914-A1 | DICHROIC MIXTURE | Rolic AG (CH) | 2004-02-04 | — | — | EP | claimed |
| WO-2004005284-A1 | SUBSTITUTED 3-CYANOQUINOLINES AS MEK INHIBITORS | ASTRAZENECA AB (SE) | 2004-01-15 | — | — | WO | claimed |
| WO-2002090447-A1 | DICHROIC MIXTURE | ROLIC AG (CH) | 2002-11-14 | — | — | WO | claimed |
| EP-1256602-A1 | Dichroic mixture | Rolic AG (CH) | 2002-11-13 | — | — | EP | claimed |
| US-6017931-A | Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines | FMC CORPORATION | 2000-01-25 | — | — | US | claimed |
| US-5888475-A | KIT FOR RAPID SYNTHESIS OF LABELED COCAINE DERIVATIVES THAT BIND DOPAMINE TRANSPORTER, COMPRISING SAID COCAINE DERIVATIVE, PHASE TRANSFER CATALYST, RADIOACTIVELY LABELED POTASSIUM FLUORIDE | EMORY UNIVERSITY (US) | 1999-03-30 | — | — | US | claimed |