Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.49 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5618248 | 0.88 | TLR8 (0.46) | TLR7TLR8NUDT1 | |
| SCHEMBL4241146 | 0.87 | TLR8 (0.49) | TLR7TLR8NUDT1 | |
| SCHEMBL5617532 | 0.87 | TLR8 (0.45) | TLR7TLR8NUDT1 | |
| SCHEMBL4245057 | 0.87 | TLR7 (0.46) | TLR7TLR8NUDT1 | |
| SCHEMBL4240706 | 0.85 | TLR8 (0.44) | TLR7TLR8NUDT1 | |
| SCHEMBL4543713 | 0.84 | TLR7 (0.58) | TLR7TLR8NUDT1 | |
| SCHEMBL4244103 | 0.83 | TLR8 (0.42) | TLR7TLR8NUDT1 | |
| SCHEMBL4243570 | 0.82 | TLR7 (0.47) | TLR7TLR8NUDT1 | |
| SCHEMBL14572654 | 0.81 | TLR8 (0.49) | TLR7TLR8NUDT1 | |
| SCHEMBL5618316 | 0.80 | TLR7 (0.48) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673087-A4 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2009-04-08 | — | — | EP | disclosed |
| EP-1673087-A2 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005032484-A2 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-04-14 | — | — | WO | disclosed |