SCHEMBL4252102

SCHEMBL4252102

COC(=O)c1cc(=O)c2ccc([N+](=O)[O-])cc2o1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.64
LMNA P02545 3/20 0.50
CYP1A2 P05177 1/20 0.50
AKR1B1 P15121 4/20 0.49
ALDH1A1 P00352 3/20 0.48
THRB P10828 1/20 0.47
MAPT P10636 3/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
HPGD P15428 1/20 0.43
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
GAA P10253 1/20 0.42
MAOB P27338 1/20 0.42
HTT P42858 1/20 0.42
POLB P06746 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4258041 0.90 KDM4E (0.53) KDM4ELMNACYP1A2CA12CA9
SCHEMBL4254512 0.87 AKR1B1 (0.67) KDM4ELMNACYP1A2AKR1B1ALDH1A1
SCHEMBL4250567 0.86 KDM4E (0.47) KDM4ELMNACYP1A2AKR1B1ALDH1A1
SCHEMBL4256577 0.86 AKR1B1 (0.67) KDM4EAKR1B1ALDH1A1MAPTMEN1
SCHEMBL4253623 0.84 MAOB (0.65) KDM4ELMNACYP1A2AKR1B1ALDH1A1
SCHEMBL4246734 0.84 AKR1B1 (0.52) KDM4ELMNACYP1A2AKR1B1ALDH1A1
SCHEMBL4246750 0.83 AKR1B1 (0.61) KDM4EAKR1B1ALDH1A1MAPTMEN1
SCHEMBL4250533 0.82 MAOB (0.56) KDM4EAKR1B1ALDH1A1MAPTMEN1
SCHEMBL4249682 0.81 MAOB (0.55) KDM4EAKR1B1ALDH1A1MAPTMAOB
SCHEMBL4246759 0.81 MAOB (0.54) KDM4EAKR1B1ALDH1A1MAPTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101497571-B Process for producing chromone compound SUMITOMO CO LTD 2012-07-04 CN disclosed
CN-1911896-B Process for producing benzopyrone compound SUMITOMO CHEMICAL CO 2010-09-15 CN disclosed
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-2105431-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
CN-101497571-A Process for producing chromone compound SUMITOMO CHEMICAL CO (JP) 2009-08-05 CN disclosed
CN-100509751-C Process for producing benzopyranone compound SUMITOMO CHEMICAL CO (JP) 2009-07-08 CN disclosed
EP-1867626-A2 Process for producing chromone compound Sumitomo Chemical Company, Limited (JP) 2007-12-19 EP disclosed
CN-1911896-A Process for producing chromone compound SUMITOMO CHEMICAL CO (JP) 2007-02-14 CN disclosed
US-20060217565-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-28 US disclosed
US-7094914-B2 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-22 US disclosed
CN-1649824-A Process for producing benzopyranone compound SUMITOMO CHEMICAL CO (JP) 2005-08-03 CN disclosed
US-20050085664-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LMITED (JP) 2005-04-21 US disclosed
EP-1479667-A1 PROCESS FOR PRODUCING CHROMONE COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085664-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL KDM4E 978/4885LMNA 1091/4885CYP1A2 17/4885
US-20060217565-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL KDM4E 978/4885LMNA 1091/4885CYP1A2 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.