SCHEMBL425230

SCHEMBL425230

CCP(=O)([O-])OCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.[Ca+]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 4/20 0.51
NR1I2 O75469 1/20 0.48
KMT2A Q03164 5/20 0.43
GAA P10253 4/20 0.43
MEN1 O00255 4/20 0.43
ALDH1A1 P00352 5/20 0.42
TSHR P16473 3/20 0.42
MAPK1 P28482 3/20 0.42
MAPT P10636 3/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
BLM P54132 2/20 0.42
ATM Q13315 2/20 0.42
HIF1A Q16665 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
USP2 O75604 1/20 0.42
CYP2D6 P10635 1/20 0.42
LMNA P02545 3/20 0.41
RECQL P46063 1/20 0.41
GMNN O75496 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2802375 0.97 HMGCR (0.51) HMGCRNR1I2KMT2AGAAMEN1
Potassium Ion SCHEMBL5912028 0.97 HMGCR (0.51) HMGCRNR1I2KMT2AGAAMEN1
SCHEMBL3164392 0.83 HMGCR (0.55) HMGCRNR1I2KMT2AGAAMEN1
SCHEMBL30609756 0.83 HMGCR (0.51) HMGCRNR1I2KMT2AGAAMEN1
SCHEMBL3164387 0.83 HMGCR (0.55) HMGCRNR1I2KMT2AGAAMEN1
SCHEMBL27292871 0.83 HMGCR (0.51) HMGCRNR1I2KMT2AGAAMEN1
SCHEMBL27828580 0.83 HMGCR (0.55) HMGCRNR1I2KMT2AGAAMEN1
SCHEMBL29120699 0.82 HMGCR (0.51) HMGCRNR1I2KMT2AGAAMEN1
SCHEMBL5709910 0.82 HMGCR (0.50) HMGCRNR1I2KMT2AGAAMEN1
SCHEMBL5912031 0.82 HMGCR (0.54) HMGCRNR1I2KMT2AGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1549704-B2 STABILIZED POLYMER COMPOSITION BOREALIS TECH OY (FI) 2011-08-03 EP claimed
EP-1549704-B1 STABILIZED POLYMER COMPOSITION BOREALIS TECH OY (FI) 2006-02-15 EP claimed
EP-2729232-B1 CO2 capture in an polypropylene absorption column comprising an antioxidant AKER ENGINEERING & TECH AS (NO) 2018-02-14 EP disclosed
EP-2382260-B1 FILM EVONIK DEGUSSA GMBH (DE) 2016-06-15 EP disclosed
US-9278308-B2 Construction element for CO2 capture AKER ENGINEERING & TECHNOLOGY AS (NO) 2016-03-08 US disclosed
US-20150166749-A1 PE MIB FILM ZN/CR EVONIK OXENO GMBH (DE) 2015-06-18 US disclosed
US-9012564-B2 Polyethylene/3-substituted alkene film made with Ziegler-Natta or chromium oxide catalyst EVONIK DEGUSSA GMBH (DE) 2015-04-21 US disclosed
EP-2729232-A1 CONSTRUCTION ELEMENT FOR CO2 CAPTURE Aker Engineering & Technology AS (NO) 2014-05-14 EP disclosed
US-20140123851-A1 CONSTRUCTION ELEMENT FOR CO2 CAPTURE AKER ENGINEERING & TECHNOLOGY AS (NO) 2014-05-08 US disclosed
US-20140031505-A1 POLYOLEFIN GAS PHASE POLYMERIZATION WITH 3-SUBSTITUTED C4-10-ALKENE EVONIK OXENO GMBH (DE) 2014-01-30 US disclosed
US-8604142-B2 Polyolefin gas phase polymerization with 3-substituted C4-10-alkene EVONIK OXENO GMBH (DE) 2013-12-10 US disclosed
EP-2382246-A1 POLYOLEFIN GAS PHASE POLYMERIZATION WITH 3-SUBSTITUTED C4-10-ALKENE Evonik Oxeno GmbH (DE) 2011-11-02 EP disclosed
EP-2382247-A1 PE MIB SLURRY POLYMERIZATION Evonik Oxeno GmbH (DE) 2011-11-02 EP disclosed
EP-1549704-B2 STABILIZED POLYMER COMPOSITION BOREALIS TECH OY (FI) 2011-08-03 EP disclosed
WO-2010084054-A1 POLYOLEFIN GAS PHASE POLYMERIZATION WITH 3-SUBSTITUTED C4-10-ALKENE EVONIK OXENO GMBH (DE) 2010-07-29 WO disclosed
WO-2010084049-A1 FILM EVONIK OXENO GMBH (DE) 2010-07-29 WO disclosed
WO-2010084051-A1 PE MIB FILM ZN/CR EVONIK OXENO GMBH (DE) 2010-07-29 WO disclosed
WO-2010084047-A1 PE MIB SLURRY POLYMERIZATION EVONIK OXENO GMBH (DE) 2010-07-29 WO disclosed
US-20060122295-A1 Stabilized polymer composition BOREALIS POLYMERS OY (US) 2006-06-08 US disclosed
EP-1549704-B1 STABILIZED POLYMER COMPOSITION BOREALIS TECH OY (FI) 2006-02-15 EP disclosed