⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7156415 | 0.78 | — | — | |
| Glycerylphosphate SCHEMBL59773 | 0.78 | SMPD1 (0.37) | — | |
| Glycerylphosphate SCHEMBL28755288 | 0.76 | SMPD1 (0.35) | — | |
| Glycerylphosphate SCHEMBL28311028 | 0.76 | SMPD1 (0.35) | — | |
| Glycerylphosphate SCHEMBL28311177 | 0.76 | SMPD1 (0.35) | — | |
| Glycerylphosphate SCHEMBL9391484 | 0.76 | SMPD1 (0.35) | — | |
| Glycerylphosphate SCHEMBL2487169 | 0.76 | SMPD1 (0.35) | — | |
| Glycerylphosphate SCHEMBL14482182 | 0.76 | SMPD1 (0.35) | — | |
| Glycerylphosphate SCHEMBL2130013 | 0.76 | SMPD1 (0.35) | — | |
| Glycerylphosphate SCHEMBL28209454 | 0.76 | SMPD1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10196641-B2 | Modified oligonucleotides for telomerase inhibition | GERON CORPORATION (US) | 2019-02-05 | — | — | US | disclosed |
| US-9657296-B2 | Modified oligonucleotides for telomerase inhibition | GERON CORPORATION (US) | 2017-05-23 | — | — | US | disclosed |
| US-20170130225-A1 | MODIFIED OLIGONUCLEOTIDES FOR TELOMERASE INHIBITION | GERON CORPORATION | 2017-05-11 | — | — | US | disclosed |
| US-9404112-B2 | Modified oligonucleotides for telomerase inhibition | GERON CORPORATION (US) | 2016-08-02 | — | — | US | disclosed |
| US-9388416-B2 | Modified oligonucleotides for telomerase inhibition | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2016-07-12 | — | — | US | disclosed |
| US-9388415-B2 | Modified oligonucleotides for telomerase inhibition | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2016-07-12 | — | — | US | disclosed |
| US-20150376624-A1 | Modified Oligonucleotides for Telomerase Inhibition | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2015-12-31 | — | — | US | disclosed |
| US-20150322437-A1 | Modified Oligonucleotides for Telomerase Inhibition | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2015-11-12 | — | — | US | disclosed |
| US-20150322438-A1 | Modified Oligonucleotides for Telomerase Inhibition | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2015-11-12 | — | — | US | disclosed |
| US-20130065950-A1 | MODIFIED OLIGONUCLEOTIDES FOR TELOMERASE INHIBITION | GERON CORPORATION | 2013-03-14 | — | — | US | disclosed |
| US-20120329858-A1 | MODIFIED OLIGONUCLEOTIDES FOR TELOMERASE INHIBITION | GERON CORPORATION | 2012-12-27 | — | — | US | disclosed |
| US-20120129918-A1 | MODIFIED OLIGONUCLEOTIDES FOR TELOMERASE INHIBITION | GERON CORPORATION | 2012-05-24 | — | — | US | disclosed |
| US-20090286853-A1 | MODIFIED OLIGONUCLEOTIDES FOR TELOMERASE INHIBITION | GERON CORPORATION | 2009-11-19 | — | — | US | disclosed |
| US-7494982-B2 | Modified oligonucleotides for telomerase inhibition | GERON CORPORATION (US) | 2009-02-24 | — | — | US | disclosed |
| US-20050113325-A1 | Modified oligonucleotides for telomerase inhibition | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2005-05-26 | — | — | US | disclosed |