SCHEMBL4252755

SCHEMBL4252755

CCCCOC(=O)C=C(I)C(=O)OCCCC

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.57
TSHR P16473 5/20 0.53
HPGD P15428 1/20 0.53
HCAR2 Q8TDS4 4/20 0.50
ALDH1A1 P00352 2/20 0.45
NPSR1 Q6W5P4 3/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
APP P05067 1/20 0.38
NAAA Q02083 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ESR1 P03372 1/20 0.37
RAD52 P43351 1/20 0.36
CYP3A4 P08684 1/20 0.35
EPHX1 P07099 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4252748 1.00 ATM (0.57) ATMTSHRHPGDHCAR2ALDH1A1
SCHEMBL6003392 1.00 ATM (0.57) ATMTSHRHPGDHCAR2ALDH1A1
SCHEMBL29116506 0.96 ATM (0.53) ATMTSHRHPGDHCAR2ALDH1A1
SCHEMBL4253587 0.95 HCAR2 (0.51) ATMTSHRHPGDHCAR2ALDH1A1
SCHEMBL4253582 0.95 HCAR2 (0.51) ATMTSHRHPGDHCAR2ALDH1A1
SCHEMBL6003124 0.95 HCAR2 (0.51) ATMTSHRHPGDHCAR2ALDH1A1
SCHEMBL4248786 0.93 HCAR2 (0.53) ATMTSHRHPGDHCAR2ALDH1A1
SCHEMBL4251449 0.93 HCAR2 (0.53) ATMTSHRHPGDHCAR2ALDH1A1
SCHEMBL4251446 0.93 HCAR2 (0.53) ATMTSHRHPGDHCAR2ALDH1A1
SCHEMBL6003068 0.89 HCAR2 (0.47) ATMTSHRHPGDHCAR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2105431-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-1867626-A2 Process for producing chromone compound Sumitomo Chemical Company, Limited (JP) 2007-12-19 EP disclosed
US-7094914-B2 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-22 US disclosed
US-20050085664-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LMITED (JP) 2005-04-21 US disclosed
EP-1479667-A1 PROCESS FOR PRODUCING CHROMONE COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085664-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL ATM 1987/4885TSHR 1710/4885HPGD 775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.