SCHEMBL425350

SCHEMBL425350

O=C(O)c1cc(I)cc(I)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.56
ERN1 O75460 1/20 0.47
MAOB P27338 1/20 0.44
TP53 P04637 1/20 0.44
AKR1C4 P17516 2/20 0.42
AKR1C3 P42330 2/20 0.42
AKR1C2 P52895 2/20 0.42
AKR1C1 Q04828 2/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
HTT P42858 2/20 0.41
PDE4A P27815 1/20 0.41
BLVRB P30043 1/20 0.41
KDR P35968 1/20 0.41
HPGD P15428 4/20 0.39
HSD17B10 Q99714 3/20 0.39
THRB P10828 2/20 0.39
ALOX12 P18054 2/20 0.39
CYP2C9 P11712 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29396210 1.00 TTR (0.56) TTRERN1MAOBTP53AKR1C4
Lithium SCHEMBL410866 0.98 TTR (0.54) TTRERN1MAOBTP53AKR1C4
SCHEMBL340511 0.98 TTR (0.54) TTRERN1MAOBTP53AKR1C4
SCHEMBL27960207 0.98 TTR (0.54) TTRERN1MAOBTP53AKR1C4
SCHEMBL9403722 0.98 TTR (0.54) TTRERN1MAOBTP53AKR1C4
SCHEMBL23803707 0.98 TTR (0.54) TTRERN1MAOBTP53AKR1C4
Lithium SCHEMBL30311136 0.98 TTR (0.54) TTRERN1MAOBTP53AKR1C4
SCHEMBL9398438 0.98 TTR (0.54) TTRERN1MAOBTP53AKR1C4
SCHEMBL27658640 0.98 TTR (0.54) TTRERN1MAOBTP53AKR1C4
Water SCHEMBL9398918 0.96 TTR (0.52) TTRERN1MAOBTP53AKR1C4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
CN-119489292-A Solder paste for connection column 德山金属株式会社 2025-02-21 CN claimed
US-20250058413-A1 Solder Paste for Connection Pin DUKSAN HI METAL CO., LTD. (KR) 2025-02-20 US claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-114113370-B Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2024-03-26 CN claimed
CN-115612114-B Copolymer membrane and method for enzymatic self-assembly synthesis and application thereof 中国科学院天津工业生物技术研究所 2024-02-20 CN claimed
CN-115722210-B Recursive nanofiber-based detection material and preparation method and application thereof 广西大学 2024-02-20 CN claimed
CN-115612403-B Self-assembled strong-adhesion copolymer film, coating method and application 中国科学院天津工业生物技术研究所 2023-12-01 CN claimed
EP-3752201-B1 SUSPENSION OF NANOSCALE, ORGANIC PARTICLES AND PROCESS FOR PRODUCTION THEREOF UNIV FRIEDRICH ALEXANDER ER (DE) 2023-11-22 EP claimed
CN-116891499-A Modifier and preparation method thereof, modified inorganic flame retardant and preparation method and application thereof 株洲时代新材料科技股份有限公司 2023-10-17 CN claimed
EP-0036145-B1 AN ORALLY ADMINISTERED DRUG FORM COMPRISING A POLAR BIOACTIVE AGENT AND AN ADJUVANT INTERx RESEARCH CORPORATION (US) 1985-05-29 EP claimed
EP-0031561-B1 A RECTALLY ADMINISTERED SUPPOSITORY COMPRISING A DRUG AND AN ADJUVANT MERCK & CO. INC. (US) 1985-04-10 EP claimed
US-4470980-A Method of increasing oral absorption of β-lactam antibiotics INTERX RESEARCH CORP. (US) 1984-09-11 US claimed
US-4464363-A HYDROXY ARYL- OR HYDROXY ARALKYL ACIDS OR SALTS MERCK & CO., INC. (US) 1984-08-07 US claimed
US-4406896-A ANTIBIOTICS, ACIDS, HYDROXY MERCK & CO., INC. (US) 1983-09-27 US claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
EP-0036534-A1 An orally administrable drug form comprising a beta-lactam antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-30 EP claimed
EP-0036145-A1 An orally administered drug form comprising a polar bioactive agent and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-23 EP claimed
EP-0035770-A2 An orally administered drug form comprising a glycosidic antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-16 EP claimed
EP-0031561-A2 A rectally administered suppository comprising a drug and an adjuvant MERCK & CO. INC. (US) 1981-07-08 EP claimed