Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 7/20 | 0.75 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4262761 | 0.93 | ACACB (0.80) | ACACBIDO1 | |
| SCHEMBL4512595 | 0.89 | ACACB (0.87) | ACACB | |
| SCHEMBL4265192 | 0.87 | ACACB (0.76) | ACACB | |
| SCHEMBL4509550 | 0.86 | ACACB (1.00) | ACACB | |
| SCHEMBL4520070 | 0.85 | ACACB (0.74) | ACACB | |
| SCHEMBL4500633 | 0.84 | ACACB (0.77) | ACACB | |
| SCHEMBL4501082 | 0.84 | ACACB (0.64) | ACACB | |
| SCHEMBL4508072 | 0.83 | ACACB (1.00) | ACACB | |
| SCHEMBL4254088 | 0.83 | ACACB (0.87) | ACACB | |
| SCHEMBL4256531 | 0.83 | ACACB (0.87) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097420-A1 | SPIROKETONE ACETYL-COA CARBOXYLASE INHIBITORS | Pfizer Products Inc. (US) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008065508-A1 | SPIROKETONE ACETYL-COA CARBOXYLASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |