⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12282006 | 0.93 | KDM4E (0.65) | — | |
| SCHEMBL18526264 | 0.91 | KDM4E (0.70) | — | |
| SCHEMBL12282205 | 0.91 | KDM4E (0.70) | — | |
| SCHEMBL15888711 | 0.87 | KDM4E (0.52) | — | |
| SCHEMBL14289054 | 0.87 | KDM4E (0.52) | — | |
| SCHEMBL19982881 | 0.86 | KDM4E (0.56) | — | |
| SCHEMBL209638 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL27635101 | 0.83 | — | — | |
| SCHEMBL11382562 | 0.83 | TSHR (0.65) | — | |
| SCHEMBL15888719 | 0.82 | TSHR (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101974016-A | Amide compound and preparation method and applications thereof | TIANJIN INST PHARM RESEARCH | 2011-02-16 | — | — | CN | claimed |
| US-7214410-B2 | Process for selecting solvents for forming films of ferroelectric polymers | SHIPLEY COMPANY, L.L.C. (US) | 2007-05-08 | — | — | US | claimed |
| EP-1730141-A1 | COMPOUNDS FOR THE TREATMENT OF DISEASES | Pfizer Limited (GB) | 2006-12-13 | — | — | EP | claimed |
| CN-1780821-A | Heterocyclic kinase inhibitors. | ABBOTT LAB (US) | 2006-05-31 | — | — | CN | claimed |
| WO-2005092887-A1 | COMPOUNDS FOR THE TREATMENT OF DISEASES | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | claimed |
| US-6617483-B1 | Extractive distillation for separating a mixture of hydrocarbons with an alkylene glycol and a compatibility agent having polar parameters and hydrogen bonding parameters that result in improved separation | GAYLORD CHEMICAL CORPORATION | 2003-09-09 | — | — | US | claimed |
| US-12528816-B2 | Substituted imidazo [1,2-b] pyridazines and [1, 2, 4] triazolo [ 4,3-b] pyridazines as camkii inhibitors | CARDURION PHARMACEUTICALS, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-20250270209-A1 | LRRK2 INHIBITORS | INTERLINE THERAPEUTICS, INC. | 2025-08-28 | — | — | US | disclosed |
| US-20240315994-A1 | SMALL MOLECULE MODULATORS OF FERROPTOSIS | ARPEGGIO BIOSCIENCES, INC. | 2024-09-26 | — | — | US | disclosed |
| US-20240182474-A1 | SUBSTITUTED IMIDAZO [1,2-b] PYRIDAZINES AND [1, 2, 4] TRIAZOLO [ 4,3-b] PYRIDAZINES AS CAMKII INHIBITORS | CARDURION PHARMACEUTICALS, INC. | 2024-06-06 | — | — | US | disclosed |
| WO-2024020458-A1 | METHOD OF TREATING ORGAN DISEASES OR DISORDERS WITH ASK1 INHIBITORS | Seal Rock Therapeutics, Inc. (US) | 2024-01-25 | — | — | WO | disclosed |
| US-11795172-B2 | Substituted imidazo[1,2-b]pyridazines and [1,2,4]triazolo[4,3-b]pyridazines as CaMKII inhibitors | CARDURION PHARMACEUTICALS, INC. (US) | 2023-10-24 | — | — | US | disclosed |
| EP-4216948-A1 | FUSED HETEROARYL COMPOUNDS AND THEIR USE AS CAMKII INHIBITORS | Cardurion Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-0948587-A1 | FUEL COMPOSITIONS | Infineum Holdings BV (NL) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998016599-A1 | FUEL COMPOSITIONS | INFINEUM HOLDINGS BV (NL) | 1998-04-23 | — | — | WO | disclosed |
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |
| EP-0192255-B1 | BIS-2H-PYRROLIDINE DIONES | CIBA-GEIGY AG (CH) | 1990-08-08 | — | — | EP | disclosed |
| US-4789674-A | ALZHEIMER'S DISEASE, MEMORY, DEMENTIA | CIBA-GEIGY CORPORATION (US) | 1988-12-06 | — | — | US | disclosed |
| US-4758575-A | Bi-2H-pyrroli(di)nediones | CIBA-GEIGY CORPORATION (US) | 1988-07-19 | — | — | US | disclosed |
| EP-0192255-A2 | Bis-2H-pyrrolidine diones | CIBA-GEIGY AG (CH) | 1986-08-27 | — | — | EP | disclosed |