Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972386 | 0.78 | PPARG (0.56) | ESRRGMAPTESR1PRSS12RXFP1 | |
| SCHEMBL20764282 | 0.75 | ESRRG (0.70) | ESRRGMAPTESR1PRSS12RXFP1 | |
| SCHEMBL3980454 | 0.73 | ESRRG (0.53) | ESRRGMAPTESR1PRSS12RXFP1 | |
| SCHEMBL20764071 | 0.72 | ESRRG (0.71) | ESRRGMAPTESR1PRSS12RXFP1 | |
| SCHEMBL3973585 | 0.71 | PPARG (0.65) | ESRRGMAPTESR1PPARG | |
| SCHEMBL5983429 | 0.71 | PPARG (0.65) | ESRRGMAPTESR1PPARG | |
| SCHEMBL11826285 | 0.71 | HTR2A (0.60) | MAPTPPARGMEN1KMT2A | |
| SCHEMBL20764058 | 0.71 | KDM4E (0.68) | ESRRGMAPTESR1NPC1RAB9A | |
| SCHEMBL20764260 | 0.71 | ESRRG (0.68) | ESRRGMAPTESR1PRSS12RXFP1 | |
| SCHEMBL20764080 | 0.70 | ESRRG (0.78) | ESRRGMAPTESR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534894-B2 | Biphenyloxy-acids | WYETH (US) | 2009-05-19 | — | — | US | claimed |