Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254681 | 1.00 | NCOA3 (0.54) | NCOA3S100A4NQO2PLAUCYP2A6 | |
| SCHEMBL29846704 | 0.80 | NCOA3 (0.59) | NCOA3S100A4NQO2PLAUCYP2A6 | |
| SCHEMBL11723189 | 0.80 | NCOA3 (0.59) | NCOA3S100A4NQO2PLAUCYP2A6 | |
| SCHEMBL11723196 | 0.80 | NCOA3 (0.59) | NCOA3S100A4NQO2PLAUCYP2A6 | |
| SCHEMBL731892 | 0.74 | CYP2A6 (0.52) | NCOA3S100A4NQO2PLAUCYP2A6 | |
| SCHEMBL4254166 | 0.74 | NPC1 (0.44) | MAPTRAB9ALMNANPC1ALDH1A1 | |
| SCHEMBL4254162 | 0.74 | NPC1 (0.44) | MAPTRAB9ALMNANPC1ALDH1A1 | |
| SCHEMBL25417027 | 0.73 | PLAU (0.50) | NCOA3S100A4NQO2PLAUCYP2A6 | |
| SCHEMBL895053 | 0.73 | PLAU (0.50) | NCOA3S100A4NQO2PLAUCYP2A6 | |
| SCHEMBL34473205 | 0.73 | PLAU (0.50) | NCOA3S100A4NQO2PLAUCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268933-B2 | Polymers functionalized with polyimine compounds | BRIDGESTONE CORPORATION (JP) | 2012-09-18 | — | — | US | claimed |
| US-20090171035-A1 | POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | claimed |
| US-8268933-B2 | Polymers functionalized with polyimine compounds | BRIDGESTONE CORPORATION (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20090171035-A1 | POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |