Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 14/20 | 0.54 |
| ▸ | AKT1S1 | Q96B36 | 3/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13855514 | 0.94 | RPS6KB1 (0.60) | RPS6KB1AKT1S1HTR2C | |
| SCHEMBL13855893 | 0.80 | HTR2C (0.53) | RPS6KB1AKT1S1HTR2CKIT | |
| SCHEMBL4255375 | 0.78 | HTR2C (0.44) | RPS6KB1AKT1S1HTR2CKIT | |
| SCHEMBL4064941 | 0.76 | RPS6KB1 (0.55) | RPS6KB1HTR2CKIT | |
| SCHEMBL4246878 | 0.72 | AKT2 (0.59) | RPS6KB1HTR2CKIT | |
| SCHEMBL13229909 | 0.72 | AKT1 (0.69) | AKT1S1 | |
| Hydrochloric Acid SCHEMBL2796785 | 0.71 | AKT1 (0.68) | AKT1S1 | |
| SCHEMBL14782387 | 0.70 | RPS6KB1 (1.00) | RPS6KB1AKT1S1 | |
| SCHEMBL14785576 | 0.70 | RPS6KB1 (1.00) | RPS6KB1AKT1S1 | |
| SCHEMBL14785575 | 0.70 | RPS6KB1 (1.00) | RPS6KB1AKT1S1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124610-A1 | PHARMACEUTICAL COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124610-A1 | PHARMACEUTICAL COMPOUNDS | GRK3, GRK4, CDK1 | RPS6KB1 102/4885AKT1S1 254/4885HTR2C 686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.