SCHEMBL4255667

SCHEMBL4255667

O=C(NCCO)C(O)C(O)CO

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 0.74
MEN1 O00255 2/20 0.74
KMT2A Q03164 2/20 0.74
ALDH1A1 P00352 2/20 0.74
MAPT P10636 1/20 0.74
TSHR P16473 2/20 0.37
CYP3A4 P08684 1/20 0.37
PDE4A P27815 1/20 0.37
PTGS1 P23219 1/20 0.36
KCNH2 Q12809 1/20 0.36
ANPEP P15144 1/20 0.35
DNPEP Q9ULA0 1/20 0.35
LMNA P02545 2/20 0.34
ALDH1A2 O94788 1/20 0.32
ALDH2 P05091 1/20 0.32
ALDH1A3 P47895 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CNR1 P21554 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
SLCO1B1 Q9Y6L6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3159437 1.00 USP2 (0.74) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL14602775 0.85 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL3871043 0.85 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL8895535 0.85 USP2 (1.00) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL4949039 0.85 USP2 (0.65) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL8018571 0.85 USP2 (0.65) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL18746027 0.83 USP2 (0.68) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL18746024 0.83 USP2 (0.68) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL1569115 0.81 USP2 (0.81) USP2MEN1KMT2AALDH1A1MAPT
SCHEMBL12346228 0.81 USP2 (0.81) USP2MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2021345-A1 HYDROXYLATED AMIDE SKIN MOISTURIZER L'Oreal (FR) 2009-02-11 EP claimed
WO-2007137925-A1 HYDROXYLATED AMIDE SKIN MOISTURIZER L'OREAL (FR) 2007-12-06 WO claimed
CN-101454330-B Hydroxylated Amide Skin Moisturizer OREAL 2013-08-14 CN disclosed
CN-101454330-A Hydroxylated amide skin moisturizer OREAL (FR) 2009-06-10 CN disclosed
EP-2021345-A1 HYDROXYLATED AMIDE SKIN MOISTURIZER L'Oreal (FR) 2009-02-11 EP disclosed
WO-2007137925-A1 HYDROXYLATED AMIDE SKIN MOISTURIZER L'OREAL (FR) 2007-12-06 WO disclosed