Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257723 | 0.73 | SMN1; SMN2 (0.46) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4256484 | 0.69 | NPC1 (0.40) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1705485 | 0.69 | NPC1 (0.40) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4257672 | 0.68 | KMT2A (0.50) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1765877 | 0.67 | — | — | |
| SCHEMBL2418976 | 0.67 | JAK3 (0.44) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4252773 | 0.67 | KMT2A (0.45) | KMT2AALDH1A1 | |
| SCHEMBL11045929 | 0.66 | JAK3 (0.47) | KMT2ANPC1RAB9A | |
| SCHEMBL2425813 | 0.66 | JAK3 (0.47) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7695257 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268933-B2 | Polymers functionalized with polyimine compounds | BRIDGESTONE CORPORATION (JP) | 2012-09-18 | — | — | US | claimed |
| US-20090171035-A1 | POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | claimed |
| US-8268933-B2 | Polymers functionalized with polyimine compounds | BRIDGESTONE CORPORATION (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20090171035-A1 | POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |