Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 20/20 | 0.70 |
| ▸ | NR1H3 | Q13133 | 20/20 | 0.70 |
| ▸ | PPARG | P37231 | 3/20 | 0.62 |
| ▸ | PPARD | Q03181 | 1/20 | 0.62 |
| ▸ | PPARA | Q07869 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4268750 | 0.93 | NR1H2 (0.70) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4263791 | 0.91 | NR1H2 (0.69) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4263266 | 0.91 | NR1H2 (0.69) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4263184 | 0.91 | NR1H2 (0.69) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4263214 | 0.87 | NR1H2 (0.73) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4272808 | 0.87 | NR1H2 (0.72) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4259187 | 0.87 | NR1H2 (0.70) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1124732 | 0.86 | NR1H2 (0.71) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4018905 | 0.86 | NR1H2 (0.71) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4257899 | 0.85 | NR1H2 (0.81) | NR1H2NR1H3PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069373-A1 | Quinoline Acids | WYETH (US) | 2009-03-12 | — | — | US | claimed |
| US-20090069373-A1 | Quinoline Acids | WYETH (US) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069373-A1 | Quinoline Acids | NR1H3, NR1H2, NR1H4 | NR1H2 2/4885NR1H3 1/4885PPARG 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.