Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 13/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882846 | 0.82 | EPHX2 (0.74) | EPHX2P2RX7ALDH1A1FAAHCNR2 | |
| SCHEMBL4262549 | 0.82 | EPHX2 (0.86) | EPHX2KMT2AMEN1P2RX7ALDH1A1 | |
| SCHEMBL4259208 | 0.82 | EPHX2 (0.60) | EPHX2KMT2AMEN1P2RX7FAAH | |
| SCHEMBL4257643 | 0.81 | EPHX2 (1.00) | EPHX2P2RX7ALDH1A1FAAHCNR2 | |
| SCHEMBL4877195 | 0.77 | EPHX2 (1.00) | EPHX2P2RX7FAAHCNR2 | |
| SCHEMBL14086742 | 0.76 | EPHX2 (1.00) | EPHX2KMT2AMEN1P2RX7FAAH | |
| SCHEMBL14086741 | 0.76 | EPHX2 (1.00) | EPHX2P2RX7FAAHCNR2 | |
| SCHEMBL4879011 | 0.75 | EPHX2 (1.00) | EPHX2P2RX7FAAHCNR2 | |
| SCHEMBL4265734 | 0.75 | EPHX2 (0.67) | EPHX2P2RX7FAAHCNR2 | |
| SCHEMBL9668580 | 0.74 | EPHX2 (0.62) | EPHX2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023731-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS | ARETE THERAPEUTICS, INC. | 2009-01-22 | — | — | US | claimed |
| US-20090023731-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS | ARETE THERAPEUTICS, INC. | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023731-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS | EPHX1, EPHX2, NCEH1 | EPHX2 2/4885KMT2A 3308/4885MEN1 4139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.