SCHEMBL4257890

SCHEMBL4257890

CC(=O)CC(=O)N[SiH2]O[SiH3]

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
HTT P42858 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.30
KDM6B O15054 1/20 0.30
KDM5C P41229 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
PHF8 Q9UPP1 1/20 0.30
KDM2A Q9Y2K7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1401066 0.70 MGAM (0.45) MGAMGAASIMGAM2HTT
SCHEMBL16754900 0.70
SCHEMBL543025 0.67
SCHEMBL30901498 0.66 MGAM (0.53) MGAMGAASIMGAM2HTT
SCHEMBL15858411 0.66
SCHEMBL7162568 0.66 CRBN (0.43) MGAMGAASIMGAM2HTT
SCHEMBL11462728 0.66
SCHEMBL9995214 0.64
Acetoacetic Acid SCHEMBL8036123 0.64 EGLN1 (0.46) MGAMGAASIMGAM2HTT
SCHEMBL10389469 0.62 MGAM (0.56) MGAMGAASIMGAM2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2054204-B1 METHOD FOR WATERPROOFING WOOD WACKER CHEMIE AG (DE) 2009-12-23 EP disclosed
US-20090191344-A1 Method for waterproofing wood WACKER CHEMIE AG (DE) 2009-07-30 US disclosed
EP-2054204-A1 METHOD FOR WATERPROOFING WOOD Wacker Chemie AG (DE) 2009-05-06 EP disclosed
WO-2008022906-A1 METHOD FOR WATERPROOFING WOOD WACKER CHEMIE AG (DE) 2008-02-28 WO disclosed
US-20080045672-A1 Chelate Polymerization WACKER CHEMIE AG (DE) 2008-02-21 US disclosed
EP-1889868-A1 Polymer containing compositions Wacker Chemie AG (DE) 2008-02-20 EP disclosed