Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 17/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476359 | 0.76 | HRH4 (0.50) | HRH4 | |
| SCHEMBL3476796 | 0.73 | NMT1 (0.35) | — | |
| SCHEMBL3475980 | 0.73 | HRH4 (0.56) | HRH4 | |
| SCHEMBL4258986 | 0.68 | NPC1 (0.43) | NPY1RHRH4 | |
| SCHEMBL13183868 | 0.64 | HRH4 (0.51) | NPY1RHRH4 | |
| SCHEMBL3476481 | 0.64 | HRH4 (0.52) | HRH4 | |
| SCHEMBL3476444 | 0.63 | HRH4 (0.55) | HRH4 | |
| SCHEMBL604528 | 0.62 | HRH4 (0.58) | NPY1RHRH4 | |
| SCHEMBL3475562 | 0.61 | HRH4 (0.57) | HRH4 | |
| SCHEMBL2566023 | 0.61 | NPY1R (0.52) | NPY1RHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009532367-A | — | — | 2009-09-10 | — | — | JP | claimed |
| EP-2004188-A4 | BENZOIMIDAZOL-2-YL PYRIDINES AS MODULATORS OF THE HISTAMINE H4 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-22 | — | — | EP | claimed |
| EP-2004188-A2 | BENZOIMIDAZOL-2-YL PYRIDINES AS MODULATORS OF THE HISTAMINE H4 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-12-24 | — | — | EP | claimed |
| WO-2007117400-A2 | BENZOIMIDAZOL-2-YL PYRIDINES AS MODULATORS OF THE HISTAMINE H4 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-10-18 | — | — | WO | claimed |