Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374958 | 0.93 | MME (0.36) | MME | |
| SCHEMBL2132240 | 0.93 | MME (0.36) | MME | |
| SCHEMBL30559586 | 0.93 | MME (0.36) | MME | |
| SCHEMBL2132230 | 0.93 | MME (0.36) | MME | |
| SCHEMBL3080046 | 0.92 | MME (0.37) | MME | |
| SCHEMBL3080050 | 0.92 | MME (0.37) | MME | |
| SCHEMBL29391135 | 0.91 | MME (0.39) | MME | |
| SCHEMBL30666390 | 0.91 | MME (0.37) | MME | |
| SCHEMBL30272502 | 0.91 | MME (0.34) | MME | |
| SCHEMBL29630312 | 0.91 | MME (0.34) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10335372-B2 | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases | Appelbaum, Jacob G. (US) | 2019-07-02 | — | — | US | disclosed |
| US-20170209376-A1 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | NANONASE, INC. | 2017-07-27 | — | — | US | disclosed |
| US-9592277-B2 | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases | AVIRID, INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-20090047272-A1 | Compositions with Modified Nucleases Targeted to Viral Nucleic Acids and Methods of Use for Prevention and Treatment of Viral Diseases | NANONASE, INC. | 2009-02-19 | — | — | US | disclosed |