Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL564170 | 0.80 | — | — | |
| SCHEMBL5488959 | 0.80 | TSHR (0.43) | TSHRTP53TDP1CYP3A4PPARD | |
| SCHEMBL28639056 | 0.78 | TSHR (0.55) | TSHRTP53TDP1PPARD | |
| SCHEMBL28829611 | 0.78 | TSHR (0.55) | TSHRTP53TDP1PPARD | |
| SCHEMBL5485248 | 0.75 | CYP3A4 (0.48) | TSHRCYP3A4 | |
| SCHEMBL5491463 | 0.75 | CYP3A4 (0.48) | TSHRTP53TDP1CYP3A4 | |
| SCHEMBL575364 | 0.75 | CYP3A4 (0.42) | TSHRTP53TDP1CYP3A4PPARD | |
| SCHEMBL3803539 | 0.75 | — | — | |
| SCHEMBL2487795 | 0.75 | — | — | |
| SCHEMBL27401476 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829104-B2 | Styrene-based resin composition, and resin molded article comprising same | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2014-09-09 | — | — | US | disclosed |
| US-20130012646-A1 | STYRENE-BASED RESIN COMPOSITION, AND RESIN MOLDED ARTICLE COMPRISING SAME | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2013-01-10 | — | — | US | disclosed |
| WO-2009118712-A2 | NOVEL DIHYDROXYPYRROLIDINE DERIVATIVES AS ANTI-CANCER AGENTS | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2009-10-01 | — | — | WO | disclosed |