Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TRAP1 | Q12931 | 5/20 | 0.37 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8203249 | 0.89 | DPP8 (0.40) | DPP8DPP9DPP7HRH3TRAP1 | |
| SCHEMBL4261537 | 0.88 | DPP8 (0.41) | DPP8DPP9DPP7HRH3ALDH1A1 | |
| SCHEMBL14963380 | 0.87 | DDB1 (0.43) | DPP8DPP9DPP7TRAP1HSP90B1 | |
| SCHEMBL2154075 | 0.87 | DDB1 (0.43) | DPP8DPP9DPP7TRAP1HSP90B1 | |
| SCHEMBL1082163 | 0.87 | DDB1 (0.43) | DPP8DPP9DPP7TRAP1HSP90B1 | |
| SCHEMBL6912998 | 0.87 | DDB1 (0.43) | DPP8DPP9DPP7TRAP1HSP90B1 | |
| SCHEMBL13223027 | 0.87 | DPP8 (0.41) | DPP8DPP9DPP7TRAP1HSP90B1 | |
| SCHEMBL9978699 | 0.85 | DDB1 (0.41) | DPP8DPP9DPP7HRH3ALDH1A1 | |
| SCHEMBL9978696 | 0.85 | DDB1 (0.41) | DPP8DPP9DPP7HRH3ALDH1A1 | |
| SCHEMBL12725885 | 0.80 | DDB1 (0.44) | TRAP1NAMPTPOLBABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046098-A1 | NOVEL CYCLIC BORONATE INHIBITORS OF HCV REPLICATION | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-09 | — | — | WO | disclosed |