Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PIKFYVE | Q9Y2I7 | 8/20 | 0.48 |
| ▸ | FES | P07332 | 1/20 | 0.48 |
| ▸ | FER | P16591 | 1/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
| ▸ | FRK | P42685 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426309 | 1.00 | MAPT (0.49) | MAPTKDM4ELMNAHPGDPIKFYVE | |
| SCHEMBL429005 | 0.92 | MAPT (0.48) | MAPTKDM4ELMNAHPGDPIKFYVE | |
| SCHEMBL429006 | 0.92 | MAPT (0.48) | MAPTKDM4ELMNAHPGDPIKFYVE | |
| SCHEMBL425398 | 0.91 | MAPT (0.49) | MAPTKDM4ELMNAHPGDPIKFYVE | |
| SCHEMBL424178 | 0.90 | PIKFYVE (0.45) | MAPTKDM4ELMNAHPGDPIKFYVE | |
| SCHEMBL424177 | 0.90 | PIKFYVE (0.45) | MAPTKDM4ELMNAHPGDPIKFYVE | |
| SCHEMBL4404371 | 0.89 | MAPT (0.51) | MAPTKDM4ELMNAHPGDPIKFYVE | |
| SCHEMBL425396 | 0.87 | MAPT (0.51) | MAPTKDM4ELMNAHPGDPIKFYVE | |
| SCHEMBL425397 | 0.87 | MAPT (0.51) | MAPTKDM4ELMNAHPGDPIKFYVE | |
| SCHEMBL429007 | 0.86 | KDM4E (0.51) | MAPTKDM4ELMNAHPGDPIKFYVE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021434-A1 | METHOD FOR TREATING B CELL REGULATED AUTOIMMUNE DISORDERS | SYNTA PHARMACEUTICALS CORP. (US) | 2012-01-26 | — | — | US | disclosed |