SCHEMBL4264196

SCHEMBL4264196

CC=CC(=O)OCCC[Si](OCC)(OCC)OCCO

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.41
HCAR2 Q8TDS4 5/20 0.37
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TSHR P16473 2/20 0.33
HPGD P15428 1/20 0.33
APP P05067 7/20 0.32
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37109 0.93 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL1132928 0.88 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL3988743 0.87 ATM (0.39) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL20357247 0.87 HCAR2 (0.45) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL25317335 0.87 HCAR2 (0.45) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL25317040 0.87 HCAR2 (0.45) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL27197554 0.87 HCAR2 (0.45) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL25316316 0.87 HCAR2 (0.45) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL10896413 0.85 ATM (0.43) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL72842 0.85 ATM (0.50) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008149375-A1 IMPROVED ORGANOSILICON COMPOUNDS RANKA, SEEMA, AJAY (IN) 2008-12-11 WO claimed
US-20080009644-A1 Organosilicon Compounds ZYDEX INDUSTRIES 2008-01-10 US claimed
US-7553983-B2 Organosilicon compounds ZYDEX INDUSTRIES (IN) 2009-06-30 US disclosed
US-20080009644-A1 Organosilicon Compounds ZYDEX INDUSTRIES 2008-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080009644-A1 Organosilicon Compounds CUL1, CUL3, MGAM ATM 3657/4885HCAR2 4492/4885MAPT 2267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.