Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576437 | 0.87 | CA12 (0.35) | CA12CA1CA2CA9 | |
| SCHEMBL3576434 | 0.87 | CA12 (0.35) | CA12CA1CA2CA9 | |
| SCHEMBL3213174 | 0.77 | CA12 (0.35) | CA12CA1CA2CA9 | |
| SCHEMBL3213162 | 0.77 | CA12 (0.35) | CA12CA1CA2CA9 | |
| SCHEMBL9666515 | 0.70 | — | — | |
| SCHEMBL13404834 | 0.69 | CYP2A6 (0.43) | CA12CA1CA2CA9 | |
| SCHEMBL9665817 | 0.67 | — | — | |
| SCHEMBL4257558 | 0.66 | — | — | |
| SCHEMBL4264969 | 0.65 | MAPT (0.32) | — | |
| SCHEMBL9665942 | 0.64 | GSK3B (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499622-B1 | HETEROTRICYCLYL 6-ALKYLIDENE-PENEMS AS BETA-LACTAMASE INHIBITORS | WYETH CORP (US) | 2009-03-11 | — | — | EP | claimed |