SCHEMBL4266702

SCHEMBL4266702

CC(C)(C)c1ccc(-c2c3nc(c(-c4ccccc4)c4ccc([nH]4)c(-c4ccc(C(C)(C)C)cc4)c4nc(cc5ccc2[nH]5)C=C4)C=C3)cc1

nearest known ligand 0.69

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.69
▸ STAT1 P42224 1/20 0.69
▸ TOP1 P11387 4/20 0.43
▸ CYCS P99999 4/20 0.42
▸ TERT O14746 3/20 0.41
▸ CNR1 P21554 1/20 0.41
▸ CNR2 P34972 1/20 0.41
▸ GPR55 Q9Y2T6 1/20 0.41
▸ HDAC6 Q9UBN7 1/20 0.40
▸ ENPP2 Q13822 1/20 0.39
▸ TNKS O95271 1/20 0.38
▸ TNKS2 Q9H2K2 1/20 0.38
▸ ABCG2 Q9UNQ0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4268662 0.99 STAT3 (0.67) STAT3STAT1TOP1CYCSTERT
SCHEMBL30527240 0.92 STAT3 (0.67) STAT3STAT1TOP1CYCSTERT
SCHEMBL30527241 0.91 STAT3 (0.66) STAT3STAT1TOP1CYCSTERT
SCHEMBL24270402 0.89 STAT3 (0.82) STAT3STAT1TOP1CYCSTERT
SCHEMBL30293296 0.89 STAT3 (0.86) STAT3STAT1TOP1CYCSTERT
SCHEMBL31550992 0.89 STAT3 (0.86) STAT3STAT1TOP1CYCSTERT
SCHEMBL1224432 0.89 STAT3 (0.86) STAT3STAT1TOP1CYCSTERT
SCHEMBL31324939 0.88 STAT3 (0.84) STAT3STAT1TOP1CYCSTERT
SCHEMBL31324940 0.88 STAT3 (0.84) STAT3STAT1TOP1CYCSTERT
SCHEMBL17841775 0.88 STAT3 (0.84) STAT3STAT1TOP1CYCSTERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7518905-B2 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-04-14 — — US disclosed
US-20060209587-A1 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-09-21 — — US disclosed
US-7042755-B1 High density non-volatile memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-05-09 — — US disclosed
WO-2001003126-A9 HIGH DENSITY NON-VOLATILE MEMORY DEVICE UNIV CALIFORNIA (US) 2002-08-01 — — WO disclosed
US-6324091-B1 Tightly coupled porphyrin macrocycles for molecular memory storage THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2001-11-27 — — US disclosed
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