⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL28508096 | 0.97 | — | — | |
| Thiourea SCHEMBL28499559 | 0.87 | CYP19A1 (0.39) | — | |
| SCHEMBL28502262 | 0.87 | CYP19A1 (0.39) | — | |
| SCHEMBL27461398 | 0.79 | CYP19A1 (0.44) | — | |
| SCHEMBL17902707 | 0.79 | — | — | |
| SCHEMBL2456178 | 0.77 | CYP19A1 (0.48) | — | |
| Ethoxycarbonyl Group SCHEMBL28308934 | 0.76 | CYP17A1 (0.35) | — | |
| SCHEMBL14048498 | 0.75 | CYP17A1 (0.43) | — | |
| SCHEMBL27749560 | 0.75 | CYP17A1 (0.43) | — | |
| SCHEMBL7553554 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112194634-B | Preparation method of N-difluoromethyl imidazole sulfur (selenium) urea derivative | 华南农业大学 | 2022-08-12 | — | — | CN | claimed |
| CN-106831599-B | A method of synthesis 1- difluoromethyl imidazole and its derivants | 南京理工大学 | 2019-08-23 | — | — | CN | claimed |
| CN-106831599-A | A kind of method for synthesizing 1 difluoromethyl imidazole and its derivants | 南京理工大学 | 2017-06-13 | — | — | CN | claimed |
| US-20250320213-A1 | Nitrogen-Containing Heterocyclic Compounds | PFIZER INC. (US) | 2025-10-16 | — | — | US | disclosed |
| US-20250171434-A1 | SEC61 INHIBITORS AND USE THEREOF | ENODIA THERAPEUTICS SAS (FR) | 2025-05-29 | — | — | US | disclosed |
| CN-119371444-A | Difluoromethyl substituted imidazole carbene metal complex and preparation method and application thereof | 中国人民大学 | 2025-01-28 | — | — | CN | disclosed |
| CN-115960055-B | N-difluoromethyl benzothiazole/oxazolselenone compound, and preparation method and application thereof | 华南农业大学 | 2024-05-10 | — | — | CN | disclosed |
| US-11814364-B2 | Pyridine N-oxide derivatives useful as factor XIa inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-14 | — | — | US | disclosed |
| CN-114685495-B | N-difluoromethyl diazacyclo selenourea compound with insecticidal, bacteriostatic, herbicidal and anticancer effects and preparation and application thereof | 华南农业大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-115960055-A | N-difluoromethyl benzothiazole/oxazole selenone compound and preparation method and application thereof | 华南农业大学 | 2023-04-14 | — | — | CN | disclosed |
| US-20230091768-A1 | PYRIDINE N-OXIDE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS | JANSSEN RESEARCH & DEVELOPMENT, LLC | 2023-03-23 | — | — | US | disclosed |
| WO-2001081332-A2 | 2-FLUOROBENZENESULFONYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2001-11-01 | — | — | WO | disclosed |
| EP-0816363-B1 | 1,2,3-Benzothiadiazole derivatives and their use as microbicides | BAYER AGROCHEM KK (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-6153763-A | A MICROBICIDES COMPRISING AN IMIDAZOLE RING | NIHON BAYER AGROCHEM K.K. | 2000-11-28 | — | — | US | disclosed |
| US-5869508-A | MICROBIOCIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1999-02-09 | — | — | US | disclosed |
| US-5849767-A | Chloropyridylcarbonyl derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1998-12-15 | — | — | US | disclosed |
| CN-1172111-A | 1, 2, 3 -benzothiadiazole derivatives | BAYER AGROCHEM KK (JP) | 1998-02-04 | — | — | CN | disclosed |
| EP-0816363-A1 | 1,2,3-Benzothiadiazole derivatives and their use as microbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1998-01-07 | — | — | EP | disclosed |
| CN-1147505-A | Chloropyridylcarbonylazoles and fungicides for agriculture and horticulture | BAYER AGROCHEM KK (JP) | 1997-04-16 | — | — | CN | disclosed |
| EP-0763530-A1 | Chloropyridylcarbonyl derivatives and their use as microbiocides | NIHON BAYER AGROCHEM K.K. (JP) | 1997-03-19 | — | — | EP | disclosed |